Efficacy of Surgery for Idiopathic Toe Walking

NCT ID: NCT06610591

Last Updated: 2024-09-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-09-09

Study Completion Date

2026-09-01

Brief Summary

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BACKGROUND:

For children who walk on their tip toes, surgery is often done to lengthen their Achilles Tendon. However, there is little research to help children's surgeons choose which children with idiopathic toe walking should have surgery.

METHODS:

This research study will investigate how effective surgery to lengthen the Achilles Tendon is for children with idiopathic toe walking. It will explore if the children\'s quality of life, endurance, strength, range of movement or walking pattern improves after they have had surgery.

This study is a pilot study with 20 participants. This means the results will be used to decide if a larger trial is needed.

Detailed Description

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BACKGROUND:

It is common for children who learn to walk to walk on their tiptoes to help with their balance. However, approximately 7% of children will continue to walk on their toes past the age of three, with no diagnosis to explain why. This is called as idiopathic toe walking and can cause problems with balance, pain and playing sports.

For children with idiopathic toe walking who cannot touch their heels to the floor in standing, surgery is often done to lengthen their Achilles Tendon. This makes it easier to bend their foot towards their shin. They should then be able to walk. with their heels down in a more typical walking pattern.

However, this improvement is not always long-term. Some children experience problems after surgery, including weak legs. There is little research to help children's surgeons choose which children with idiopathic toe walking should have surgery.

METHODS:

This research study will investigate how effective surgery to lengthen the Achilles Tendon is for children with idiopathic toe walking. It will take part in two hospitals, Oxford University Hospitals and St George\'s Hospitals. It will explore if the children\'s quality of life, endurance, strength, range of movement or walking pattern improves after they have had surgery. This study is a pilot study. This means it is a smaller trial with 20 participants. The results will be used to decide if a larger trial is needed, and how a larger trial should be run.

The children in the study will be 8-16 years old, with a tight Achilles Tendon, who have been selected for surgery. They will receive usual care. This means their surgery will be no different than if they were not included in the study.

The children will be given questionnaires with a maximum of 22 questions before surgery, six months after surgery and one year after surgery. They will also do a single heel-rise test before surgery and one year after surgery. This will test if their calf muscle strength has changed after surgery. They will also complete a computerised walking analysis before surgery and one year after surgery. This will test if their walking pattern has changed after surgery. They will also complete a satisfaction questionnaire one year after surgery. This will ask about how satisfied they are with the surgery.

Conditions

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Idiopathic Toe-walking

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Achilles Lengthening Surgery

Participants will receive Achilles lengthening surgery, as usual care.

Achilles Lengthening Surgery

Intervention Type PROCEDURE

The procedure is undertaken under general anaesthetic and involves horizontal hemi-section of the Achilles tendon via small 'stab' incisions at three levels to effect a lengthening of the tendon. The patient is then placed in a walking cast for four weeks thereafter. This surgery is usual care for most children with symptomatic ITW with plantarflexion contractures who have failed non-operative management.

Interventions

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Achilles Lengthening Surgery

The procedure is undertaken under general anaesthetic and involves horizontal hemi-section of the Achilles tendon via small 'stab' incisions at three levels to effect a lengthening of the tendon. The patient is then placed in a walking cast for four weeks thereafter. This surgery is usual care for most children with symptomatic ITW with plantarflexion contractures who have failed non-operative management.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Children aged 8-16 at recruitment.
* Idiopathic toe walkers based on clinicians' assessment.
* Plantarflexion contracture with knee extended of 0 degrees or less of dorsiflexion.
* Listed for surgical lengthening of the plantarflexors.

Exclusion Criteria

* Unable to give informed assent or consent. Previous surgery to the lower limb.
* Unable to effectively participate in gait analysis (e.g. unable to walk 10-metres unaided, unable to walk independently, allergy to adhesive for skin markers, hyperhidrosis).
* Underlying diagnoses which may cause toe walking (e.g. muscular dystrophy, split cord malformation, cerebral palsy).
* Listed for additional procedures in the surgery for the lengthening of the plantarflexors.
* Awaiting further investigations or neurology assessment for toe walking pattern.
Minimum Eligible Age

8 Years

Maximum Eligible Age

16 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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British Society for Children's Orthopaedic Surgery

UNKNOWN

Sponsor Role collaborator

University of Oxford

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Alpesh Kothari, MA, BM, BCh, AFHEA, MSc, DPhil

Role: PRINCIPAL_INVESTIGATOR

University of Oxford

Yael Gelfer, BSc, MD, PhD, FRCS

Role: STUDY_DIRECTOR

St George's University Hospitals NHS Foundation Trust

Julie Stebbins, DPhil SRCS CSci

Role: STUDY_DIRECTOR

University of Oxford

Locations

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St George's University Hospitals NHS Foundation Trust

Tooting, London, United Kingdom

Site Status RECRUITING

Oxford University Hospitals NHS Foundation Trust

Oxford, Oxfordshire, United Kingdom

Site Status RECRUITING

Countries

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United Kingdom

Central Contacts

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Eileen M Morrow, BSc. MSc.

Role: CONTACT

+441865 227 607

Facility Contacts

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Yael Gelfer, BSc, MD, PhD, FRCS

Role: primary

+4420 8725 6749

Eileen M Morrow, BSc. MSc.

Role: primary

+44 1865 227 607

Other Identifiers

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PID:17261

Identifier Type: -

Identifier Source: org_study_id

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