Evaluation of Updated Procedure for Management of Refractory Out-of-hospital Cardiac Arrests

NCT ID: NCT06603649

Last Updated: 2024-09-19

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Total Enrollment: 150 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2024-10-01
• Study Completion Date: 2030-12-31

Brief Summary

ECPR is a technique that has been rapidly developed in many cardiac arrest specialized centers In 2013, a specific management protocol was developed for patients in refractory out-of-hospital cardiac arrest around Nancy, France. To select patients with the best prognosis, the inclusion criteria defined were strict. This led to an over-selection of patients and a significant reduction in the number of eligible patients. A balance needed to be struck between over-selecting patients and maintaining the expertise of medical and paramedical teams in the field. In addition, it has also been shown that ECPR also increases the number of organs and transplants.

In February 2024, the criteria for inclusion in the protocol were redefined to include any witnessed non-traumatic cardiac arrest, whatever the initial rhythm. This simplification should enable more patients to be included in the procedure.

The aim of the study is to assess the patient's outcome

Conditions

Cardiac Arrest, Out-Of-Hospital

Study Design

• Observational Model Type: CASE_ONLY
• Study Time Perspective: RETROSPECTIVE

Interventions

ECPR for out-of-hospital cardiac arrest

Patient with out-of-hospital cardiac arrest enrolled in the ECPR protocol

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Out-of-hospital cardiac arrest
• enrolled in the ECPR program
• 18 years old or more
• Low-flow estimated <60minutes

Exclusion Criteria

• traumatic cardiac arrest
• major comorbidities

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Central Hospital, Nancy, France

OTHER

Sponsor Role: lead

Responsible Party

JAEGER Deborah

Principal investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

CHRU

Nancy, , France

Countries

France

Facility Contacts

Deborah Jaeger, MD, PhD

Role: primary

d.jaeger@chru-nancy.fr

Other Identifiers

2024PI049

Identifier Type: -

Identifier Source: org_study_id