Nailfold Capillaroscopic Pattern Changes and Its Correlation with Interstitial Lung Disease (ILD) in Systemic Sclerosis (SSc) Patients.
NCT ID: NCT06579651
Last Updated: 2024-08-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
45 participants
OBSERVATIONAL
2024-10-31
2025-11-30
Brief Summary
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Detailed Description
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Nailfold videocapillaroscopy (NVC) is the validated technique to assess SSc microvascular damage and is useful for the early diagnosis and follow-up of SSc micro- angiopathy.
Several studies have demonstrated correlations between microvascular damage extent and the severity of internal organ involvement, showing that NVC abnormalities correlate with disease activity and severity and may be also predictive for disease worsening. Furthermore, successful treatments have been shown to reduce NVC abnormalities in SSc cases, and these findings support the importance of NVC in monitoring SSc patients and also suggest its possible role as an outcome measure for microangiopathy in clinical trials.
Three different NVC patterns of microvascular damage have been described (\"early\" , \"active\" , \"late\" ).
Conditions
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Study Design
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CASE_ONLY
CROSS_SECTIONAL
Interventions
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Nailfold videocapillaroscopy (NVC)
Nailfold videocapillaroscopy (NVC) is the validated technique to assess SSc microvascular damage and is useful for the early diagnosis and follow-up of SSc micro- angiopathy.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
3-Congestive heart failure and presence of clubbing. 4-history of smoking. 5-Patients unable to co-operate for nail fold capillaroscopic examination.
18 Years
75 Years
ALL
No
Sponsors
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Assiut University
OTHER
Responsible Party
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Mennatullah Salaheldin
Mennatullah Salaheldin Mohamed
Central Contacts
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Other Identifiers
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NVC in SSc patients
Identifier Type: -
Identifier Source: org_study_id