Associative Peripheral Stimulation for Reduction of Motor Impairment During Acute Period of Stroke Recovery

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-12-18

Study Completion Date

2024-12-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Associative Peripheral Stimulation (APS) is a non-invasive therapy intended for stroke rehabilitation involving transcutaneous electrical muscle stimulation paired with voluntary movement. This pilot study investigates whether APS applied during the acute phase of stroke recovery may reduce impairment and improve function in the affected upper extremity.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Comparison of Four-Channel Functional Electrical Stimulation vs. One-Channel Electrical Stimulation on Moderate Arm/Hand Paresis in Subacute Stroke Patients

NCT07098572

Moderate Arm Paresis Ischemic Stroke

RECRUITING NA

Functional Electrical Stimulation (FES) for Upper Extremity Recovery in Stroke

NCT00142792

Stroke, Acute Stroke Hemiparesis

COMPLETED NA

Combined Antagonistic Muscle Magnetic Stimulation and Selective Periferal Neurotomy to Improve Results on Spasticity

NCT02226432

STROKE

NOT_YET_RECRUITING NA

Effects of Accelerated Skill Acquisition Programme With Segmental Vibration on Upper Limb in Stroke.

NCT07128823

Subacute Stroke

RECRUITING NA

Peripheral Nerve Stimulation to Improve Upper Extremity Function After Severe Stroke

NCT04576013

Stroke

TERMINATED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Stroke Stroke, Acute Stroke, Ischemic Stroke, Hemorrhagic Hemiparesis Hemiparesis;Poststroke/CVA Weakness of Extremities as Sequela of Stroke Stroke Sequelae Upper Extremity Paresis

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Caregivers Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Group A

Treatment

Group Type EXPERIMENTAL

Associative Peripheral Stimulation (APS) 1.0

Intervention Type DEVICE

Associative peripheral stimulation paired with rehabilitative exercises.

Group B

Control

Group Type ACTIVE_COMPARATOR

Peripheral Neuromuscular Stimulation

Intervention Type DEVICE

Random peripheral stimulation paired with rehabilitative exercises.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Associative Peripheral Stimulation (APS) 1.0

Associative peripheral stimulation paired with rehabilitative exercises.

Intervention Type DEVICE

Peripheral Neuromuscular Stimulation

Random peripheral stimulation paired with rehabilitative exercises.

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

1. Confirmed ischemic or hemorrhagic stroke no earlier than 7 days prior to enrollment;
2. Presentation of hemiparesis or paralysis of the upper extremity due to stroke;
3. Ability to comprehend and follow study instructions;
4. Ability to initiate finger extension (≥3°) at least three times per minute;
5. Fugl-Meyer Assessment (Upper Extremity) score of \<47.

Exclusion Criteria

1. Contraindications, intolerance, or high sensitivity to the experimental protocol;
2. History of upper-extremity disability prior to the index stroke;
3. Neurological conditions (other than stroke) affecting motor function;
4. Treatment of spasticity/increased tone in the affected upper extremity (e.g., with Botox injection);
5. Lack of access to a safe and suitable place of discharge for experimental sessions and follow-up visits.

Minimum Eligible Age

18 Years

Maximum Eligible Age

79 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No