BOOM-IBD2 Pivotal Clinical Trial

NCT ID: NCT06571669

Last Updated: 2025-07-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

137 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-01-31

Study Completion Date

2026-10-31

Brief Summary

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The BOOM-IBD2 clinical trial is designed to evaluate the effectiveness of sacral neuromodulation for the treatment of IBD.

Detailed Description

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Conditions

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Ulcerative Colitis Inflammatory Bowel Diseases

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Treatment Arm

Patients implanted with neuromodulation

Group Type EXPERIMENTAL

Neuromodulation

Intervention Type DEVICE

Neuromodulation

Interventions

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Neuromodulation

Neuromodulation

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Male or female
* 18 to 85 years of age
* Diagnosed with ulcerative colitis
* Ability and willingness to consent to participate by signing the informed consent form
* Ability to comply with the protocol and willingness to comply with all follow up requirements

Exclusion Criteria

* Any significant medical condition that is likely to interfere with study procedures, device operation, or likely to confound the results of the study
* Any psychiatric or personality disorder at the discretion of the study investigator
* Any active bacterial infection with a risk of bacteremia or sepsis (e.g. presence of abscess)
* Active clostridium difficile infection of the colon
* Active cytomegalovirus (CMV) infection of the colon
* Evidence of colonic perforation
* Fulminant colitis requiring emergency surgery
* Microscopic, ischemic or infectious colitis
* Unresected neoplasia of the colon
* Colonic stricture unable to pass a colonoscope
* Current evidence of cancer in the gastrointestinal tract
* Current participation in another clinical trial
* Previous history of surgery for ulcerative colitis, or probably to require such intervention
* Previously implanted with a neurostimulation device or participated in a neurostimulation trial
* Inability to operate the patient programmer
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Boomerang Medical

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Center for Colorectal Innovation

Los Angeles, California, United States

Site Status RECRUITING

Hoag Hospital

Newport Beach, California, United States

Site Status RECRUITING

PAMF (Palo Alto Medical Foundation)

Palo Alto, California, United States

Site Status RECRUITING

Kansas Gastro

Wichita, Kansas, United States

Site Status RECRUITING

Objective Health - St. Louis

St Louis, Missouri, United States

Site Status RECRUITING

Las Vegas Medical Research LLC, DBA Vector Clinical Trials

Las Vegas, Nevada, United States

Site Status RECRUITING

Columbia University Irving Medical Center/New York Presbyterian Hospital

New York, New York, United States

Site Status RECRUITING

UNC Chapel Hill

Chapel Hill, North Carolina, United States

Site Status RECRUITING

Objective Health - Amarillo

Amarillo, Texas, United States

Site Status RECRUITING

Objective Health - Central Texas

Waco, Texas, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Malea D'Amico

Role: CONTACT

844-423-9747

Colleen Holthe

Role: CONTACT

844-423-9747

Facility Contacts

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Clinical Trial Coordinator

Role: primary

(310) 289-9224

Clinical Trial Coordinator

Role: primary

949-764-5597 ext. 45597

Clinical Research Manager

Role: primary

510-491-6606

Clinical Research Manager

Role: primary

(316) 730-1029

Clinical Trial Coordinator

Role: primary

314-779-5885

Clinical Trial Coordinator

Role: primary

+1 702-750-0222

Clinical Research Manager

Role: primary

(212) 342-4102

Clinical Trial Coordinator

Role: primary

919-966-8217

Clinical Trial Coordinator

Role: primary

806-214-2844

Role: primary

(254) 523-4187

Other Identifiers

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BOOM-IBD2 (CIP-B02)

Identifier Type: -

Identifier Source: org_study_id

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