The Effect of Colchicine on Platelet Function Profiles in Patients With Stable Coronary Artery Disease
NCT ID: NCT06567678
Last Updated: 2025-08-11
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
PHASE1
22 participants
INTERVENTIONAL
2024-08-21
2024-11-04
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Effect of Low Dose of Colchicine on Platelet Reactivity
NCT05956145
Colchicine in Belgium in Patients With Coronary Artery Disease After Percutaneous Coronary Intervention
NCT06095765
Anti-platelet Effects of Colchicine in Healthy Volunteers
NCT02140372
Colchicine for the Stability of Coronary Plaque in Acute Coronary Syndrome (COLOCT)
NCT04848857
Effects of Optimized Antiplatelet Treatment After Percutaneous Coronary Intervention
NCT00404781
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
NA
SINGLE_GROUP
TREATMENT
NONE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Colchicine 0.5mg po bd
Patients with coronary disease taking Colchicine 0.5mg twice-daily orally for two weeks
Colchicine 0.5 MG oral tablet twice daily
Blood samples will be collected from participants in 2 separate instances. Initially, a baseline VerifyNow P2Y12 PRU and Aspirin reaction unit test assay, followed by a subsequent repeat test 2-week after a 2-week, colchicine 0.5mg oral tablet twice-daily
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Colchicine 0.5 MG oral tablet twice daily
Blood samples will be collected from participants in 2 separate instances. Initially, a baseline VerifyNow P2Y12 PRU and Aspirin reaction unit test assay, followed by a subsequent repeat test 2-week after a 2-week, colchicine 0.5mg oral tablet twice-daily
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Patients older than 18 years of age.
* Patients currently on dual anti platelets, aspirin and clopidogrel
Exclusion Criteria
18 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
The University of The West Indies
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Naveen Seecheran
Principal Investigator
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Naveen Seecheran
Role: PRINCIPAL_INVESTIGATOR
The University of The west Indies, Saint Augustine, Trinidad and Tobago.
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
The University of The West Indies
Saint Augustine, , Trinidad and Tobago
Countries
Review the countries where the study has at least one active or historical site.
References
Explore related publications, articles, or registry entries linked to this study.
Seecheran N, Grimaldos K, McCallum P, Ramcharan P, Kawall J, Katwaroo A, Grimaldos G, Seecheran V, Jagdeo CL, Rafeeq S, Seecheran R, Leyva Quert A, Ali N, Peram L, Motilal S, Ramtahal R, Bhagwandass N, Giddings S, Ramlackhansingh A, Sandy S. The Effect of Colchicine on Platelet Function Profiles in Patients with Stable Coronary Artery Disease: The ECLIPSE Pilot Study. Cardiol Ther. 2025 Mar;14(1):87-100. doi: 10.1007/s40119-024-00393-2. Epub 2025 Jan 18.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
CREC-SA2525/02/2024
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.