Feasibility of Using NeuraSignal Transcranial Doppler Robot
NCT ID: NCT06565442
Last Updated: 2025-12-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
20 participants
OBSERVATIONAL
2026-02-15
2027-12-15
Brief Summary
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Detailed Description
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Cerebral autoregulation has historically been difficult to quantify, in part due to the difficulty in measuring cerebral blood flow directly. Transcranial doppler (TCD) is a well-established method of calculating cerebral blood flow based on velocity through the middle cerebral arteries, however traditional methods of performing TCD are time consuming and require technical and procedural training. It also carries the established risk of miscalculation with variation in intra-operator technique differences and miscalculations due to inappropriate angle of the probe. The NeuraSignal transcranial doppler robot offers a potential tool to make obtaining cerebral blood flow calculations easier and, with the use of AI to determine optimal windows, significantly decreases intra-operator differences and errors associated with inappropriate probe angle. Cerebral blood flow calculated in this way can then be correlated with arterial blood pressure and used to build cerebral autoregulatory curves in near real time. This study aims to build on previous studies deriving and using personalized cerebral autoregulatory curves and determine the feasibility of using the TCD robot in this way to make individualized cerebral autoregulatory curves more accessible as a tool for personalized blood pressure management.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Study Group
Using the NeuraSignal transcranial doppler robot in a neuro ICU setting to measure cerebral blood flow correlated with arterial blood pressure to generate individualized cerebral autoregulatory curves.
NeuraSignal transcranial doppler robot
measure cerebral blood flow correlated with arterial blood pressure to generate individualized cerebral autoregulatory curves
Interventions
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NeuraSignal transcranial doppler robot
measure cerebral blood flow correlated with arterial blood pressure to generate individualized cerebral autoregulatory curves
Eligibility Criteria
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Inclusion Criteria
* Patients admitted to the Neuro ICU for blood pressure management (MAP management) after spinal surgery
Exclusion Criteria
* prisoners
* pregnant women,
* non-English speaking,
* patients enrolled in concurrent
* ongoing interventional trial
* students of UAB
* employees of UAB
* targeting specific populations
* patients with previously diagnosed brain pathology
* patients with open wounds over temporal bones precluding transcranial doppler
18 Years
89 Years
ALL
No
Sponsors
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University of Alabama at Birmingham
OTHER
Responsible Party
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Emily Wasson
MD, MPH Assistant Professor Division of Critical Care Department of Anesthesiology and Perioperative Medicine
Principal Investigators
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Emily A Wasson, MD,MPH
Role: PRINCIPAL_INVESTIGATOR
University of Alabama at Birmingham
Locations
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UAB Department of Anesthesiology and Perioperative Medicine
Birmingham, Alabama, United States
Countries
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Central Contacts
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Facility Contacts
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Shanna Graves
Role: primary
Other Identifiers
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UAB
Identifier Type: OTHER
Identifier Source: secondary_id
IRB-300013270
Identifier Type: -
Identifier Source: org_study_id