The Bioavailability of Compounded and Generic Rapamycin in Normative Aging Individuals

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

67 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-04-25

Study Completion Date

2023-12-15

Brief Summary

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This study collected real-world evidence to better understand and define the relative bioavailability ratio between compounded rapamycin and generic rapamycin, with a specific focus on relative efficacy in increasing rapamycin levels in the blood (blood rapamycin levels).

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Detailed Description

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Conditions

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Aging

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Compounded Rapamycin

Participants in this group were receiving Compounded Rapamycin (dosages include 5, 10, or 15mg) once per week

Rapamycin

Intervention Type DRUG

Rapamycin in 2 different dosage forms (compounded and generic)

Generic Rapamycin

Participants in this group were receiving Generia Rapamycin (dosages include 2,3,6, or 8mg) once per week

Rapamycin

Intervention Type DRUG

Rapamycin in 2 different dosage forms (compounded and generic)

Interventions

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Rapamycin

Rapamycin in 2 different dosage forms (compounded and generic)

Intervention Type DRUG

Other Intervention Names

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Sirolimus Rapamune Rapacan Siromus Raparen Rapasim Sirova

Eligibility Criteria

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Inclusion Criteria

* Receive AgelessRx's standard Rapamycin treatment protocol
* Opted to complete at least 1 blood draw at their local Quest Lab

Exclusion Criteria

* Not approved for current AgelessRx standard Rapamycin treatment
* History of uncontrolled disease
* Unable to complete at least 1 blood draw at their local Quest Lab

Minimum Eligible Age

40 Years

Maximum Eligible Age

120 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes