Respiratory Training in Friedreich's Ataxia

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

1 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-08-29

Study Completion Date

2025-08-07

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This is a prospective interventional study of patients with Friedreich's Ataxia that receive respiratory strength training for a period of 12 weeks with two research visits at the beginning and at the end of the study period. Visits include swallowing evaluation with fiberoptic endoscopic evaluation of swallowing, pulmonary function testing, surface electromyography and patient surveys.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Exercise Training in Dystonia

NCT03318120

Dystonia

COMPLETED NA

Airway Muscle Training for Obstructive Sleep Apnea

NCT02259660

Obstructive Sleep Apnea

COMPLETED NA

Impact of Neck and Facial Exercises on Swallowing Function in Elderly Individuals

NCT06301594

Dysphagia

NOT_YET_RECRUITING NA

Expiratory Muscle Training for Persons With Neurodegenerative Disease

NCT00856518

Parkinson's Disease Multiple Sclerosis

COMPLETED PHASE2/PHASE3

Tongue Motor Recruitment During Exercise

NCT02687737

Healthy

COMPLETED NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Friedreich Ataxia

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Respiratory Strength Training (RST)

Participants will receive a respiratory strength training device to take home and use up to 5 times a week for 12 weeks.

Group Type EXPERIMENTAL

Respiratory Strength Training (RST)

Intervention Type OTHER

Respiratory Strength training involves inhaling/exhaling against a fix resistant to potentially increase respiratory strength

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Respiratory Strength Training (RST)

Respiratory Strength training involves inhaling/exhaling against a fix resistant to potentially increase respiratory strength

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* confirmed genetic testing of Friedreich's Ataxia
* have an overall DIGEST score of 1 or higher based on FEES screening
* are able to perform pulmonary function testing

Exclusion Criteria

* have been on antibiotics within 15 days prior to baseline screening.
* have been prescribed systemic corticosteroids or neuromuscular blocking agents within 15 days of the baseline screening
* have an allergy or contraindication to topical lidocaine or oxymetazoline
* have any other concurrent medical condition which, in the opinion of the investigators, would make the subject inappropriate to participate in testing or respiratory exercise

Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No