Intraperitoneal Chemotherapy in Recurrent Ovarian Cancer

NCT ID: NCT06535334

Last Updated: 2024-08-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-08-15

Study Completion Date

2026-05-31

Brief Summary

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This study aims to compare intravenous chemotherapy versus intraperitoneal chemotherapy in patients with recurrent ovarian cancer.

Detailed Description

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Conditions

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Intravenous Chemotherapy Versus Intraperitoneal Chemotherapy in Recurrent Ovarian Cancer

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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intravenous chemotherapy

triweekly chemotherapy with carboplatin AUC=5\~6 + liposomal-doxorubicin 30\~40mg/m2 or paclitaxel 175mg/m2 0r docetaxel 60\~75mg/m2

Chemotherapy

Intervention Type DRUG

Intravenous chemotherapy versus intraperitoneal chemotherapy in recurrent ovarian cancer

intraperitoneal chemotherapy

Day 1 IV Paclitaxel 135 mg/m2 + IP Cisplatin 75-100 mg/m2 or IP carboplatin (AUC = 6) Day 8 IP Paclitaxel 60 mg/m2 Every 21 days \* 6 cycles

OR

Day 1 IP Carboplatin AUC=5 or IP Cisplatin 50-75mg/m2 Day 2 IV Liposomal doxorubicin 15 mg/m2 + IP Liposomal doxorubicin 15 mg/m2 Every 28 days \* 6 cycles

Chemotherapy

Intervention Type DRUG

Intravenous chemotherapy versus intraperitoneal chemotherapy in recurrent ovarian cancer

Interventions

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Chemotherapy

Intravenous chemotherapy versus intraperitoneal chemotherapy in recurrent ovarian cancer

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* women who had recurrent ovarian cancer and was treated with either intravenous or intraperitoneal platinum based chemotherapy

Exclusion Criteria

* women who did not complete the designated treatment course (exception to those who had to quit due to progressive disease or death of any cause)
Minimum Eligible Age

20 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Far Eastern Memorial Hospital

OTHER

Sponsor Role lead

Responsible Party

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Sheng-Mou Hsiao

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Department of Obstetrics and Gynecology, Far Eastern Memorial Hospital

Banqiao District, New Taipei, Taiwan

Site Status

Countries

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Taiwan

Other Identifiers

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113130-E

Identifier Type: -

Identifier Source: org_study_id

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