Registry Study of Chinese Patients with Marginal Zone Lymphoma (MOTIVE)

NCT ID: NCT06534463

Last Updated: 2024-12-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-08-02

Study Completion Date

2029-09-01

Brief Summary

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This study aims to evaluate real-world treatment modalities and their corresponding effectiveness and safety in Chinese patients with marginal zone lymphoma, while also exploratively analyzing patient characteristics and health-related quality of life.

Detailed Description

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Conditions

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Marginal Zone Lymphoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Observational Cohort

Including newly diagnosed marginal zone lymphoma (MZL) and relapse/refractory MZL participants who meet the treatment indications for MZL and are about to undergo MZL treatment.

All treatment regimen selections and usage will be determined by the physician based on clinical practice and/or the respective drug labels in China.

Intervention Type OTHER

The dosage and duration of any drug in this study will be determined by the physician based on local clinical practice and local drug labels. The drugs in this study include, but are not limited to, Obinutuzumab, Rituximab, Bruton tyrosine kinase inhibitors, and Lenalidomide. In this non-interventional study, all treatment drug usage will be determined by the physician based on clinical practice and/or the respective drug labels in China.

Interventions

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All treatment regimen selections and usage will be determined by the physician based on clinical practice and/or the respective drug labels in China.

The dosage and duration of any drug in this study will be determined by the physician based on local clinical practice and local drug labels. The drugs in this study include, but are not limited to, Obinutuzumab, Rituximab, Bruton tyrosine kinase inhibitors, and Lenalidomide. In this non-interventional study, all treatment drug usage will be determined by the physician based on clinical practice and/or the respective drug labels in China.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Be diagnosed as MZL
* Meet the treatment indications for MZL

Exclusion Criteria

* Any reason that, in the investigator's opinion, makes the participant unsuitable to participate in this study.
Minimum Eligible Age

14 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Ruijin Hospital

OTHER

Sponsor Role lead

Responsible Party

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Zhao Weili

Deputy director of hospital

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Shanghai Ruijin Hospital

Shanghai, Shanghai Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Weili Zhao

Role: CONTACT

+862164370045 ext. 610707

Facility Contacts

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Weili Zhao, M.D. and Ph.D

Role: primary

+86021-64370045

Other Identifiers

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MOTIVE

Identifier Type: -

Identifier Source: org_study_id