Effect of Breather in COPD Patients with Intermittent Claudication

NCT ID: NCT06529185

Last Updated: 2024-12-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

60 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-07-30

Study Completion Date

2025-02-28

Brief Summary

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The aim of this study To show the effect of breather on ventilatory and vascular function in COPD patient with intermittent claudication.

Detailed Description

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recent researches show that COPD patients have risk of developing peripheral arterial disease (PAD) which represented on patient by intermittent claudication inspiratory muscle trainer as the breather device show increasing in inspiratory muscle strength and endurance; reduction of dyspnea; and improving of exercise tolerance .

Because of all this things this study tends to show the effect of the breather on ventilatory and vascular function in COPD patient with intermittent claudication.

Conditions

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COPD PAD

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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treatment group

This group include 30 patients with COPD and intermittent claudication. These patients can receive aerobic exercise (by applying treadmill exercise for 20 min) and inspiratory muscle training (by using The BREATHER device with Light/Medium resistance for 3-5 sets /session), for 4 weeks (3 sessions per week) and pursed lip breathing.

Group Type EXPERIMENTAL

The BREATHER

Intervention Type DEVICE

The BREATHER is Light/Medium resistance inspiratory muscle trainer which has significance role in increasing inspiratory muscle strength and endurance which could result in a decreased sensation of dyspnea

control group

This group include 30 patients with COPD and intermittent claudication. These patients can receive pursed lip breathing and aerobic exercise (by applying treadmill exercise for 20 min) with the usually pharmacological treatment, for 4 weeks (3 sessions per week).

Group Type ACTIVE_COMPARATOR

pharmacological treatment

Intervention Type DRUG

patient will receive the usually pharmacological treatment.

Interventions

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The BREATHER

The BREATHER is Light/Medium resistance inspiratory muscle trainer which has significance role in increasing inspiratory muscle strength and endurance which could result in a decreased sensation of dyspnea

Intervention Type DEVICE

pharmacological treatment

patient will receive the usually pharmacological treatment.

Intervention Type DRUG

Other Intervention Names

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experimental group control group

Eligibility Criteria

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Inclusion Criteria

* sixty male patients with diagnosed with grade I and grade II COPD their ages ranged between 55-60years
* All patients will be clinically and medically stable when attending the study.
* Body mass index (BMI) is 18.5 to 24.9 kg/m2.
* History of unilateral exertional leg pain,
* Ambulation during a graded treadmill test limited by leg pain consistent with intermittent claudication (stage II of the fontaine classification of pad),
* And an ankle-brachial index (ABI) of 0.90 or lower at rest or 0.73 or lower after exercise.

Exclusion Criteria

* cardiovascular insufficiency,
* Recent myocardial infarction,
* heart failure,
* arrhythmia,
* DVT,
* Intracranial hypertension,
* Pneumonia,
* kidney failure,
* fractures,
* uncooperative patients,
* cognitive impairment preventing a patient from participation in exercises.
Minimum Eligible Age

50 Years

Maximum Eligible Age

60 Years

Eligible Sex

MALE

Accepts Healthy Volunteers

No

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Reem Medhat Mohamed Ali Farahat

demonstrator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Zahra M Serry, Assist.Prof

Role: STUDY_DIRECTOR

Cairo University

MARWA M ELSAYED, Assist.Prof

Role: STUDY_DIRECTOR

Cairo University

Amira I Almeldin, Assist.Prof

Role: STUDY_DIRECTOR

Cairo University

reem M farahat, student

Role: PRINCIPAL_INVESTIGATOR

Cairo University

Locations

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Faculty of Physical Therapy

Dokki, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Reem M Farahat, student

Role: CONTACT

Phone: +201050770870

Email: [email protected]

Facility Contacts

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Reem Farahat, master

Role: primary

References

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Beaumont M, Forget P, Couturaud F, Reychler G. Effects of inspiratory muscle training in COPD patients: A systematic review and meta-analysis. Clin Respir J. 2018 Jul;12(7):2178-2188. doi: 10.1111/crj.12905. Epub 2018 May 23.

Reference Type BACKGROUND
PMID: 29665262 (View on PubMed)

Pinto B, Correia MV, Paredes H, Silva I. Detection of Intermittent Claudication from Smartphone Inertial Data in Community Walks Using Machine Learning Classifiers. Sensors (Basel). 2023 Feb 1;23(3):1581. doi: 10.3390/s23031581.

Reference Type BACKGROUND
PMID: 36772621 (View on PubMed)

Terzikhan N, Lahousse L, Verhamme KMC, Franco OH, Ikram AM, Stricker BH, Brusselle GG. COPD is associated with an increased risk of peripheral artery disease and mortality. ERJ Open Res. 2018 Dec 21;4(4):00086-2018. doi: 10.1183/23120541.00086-2018. eCollection 2018 Oct.

Reference Type BACKGROUND
PMID: 30588480 (View on PubMed)

Other Identifiers

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Breather on COPD with IC

Identifier Type: -

Identifier Source: org_study_id