Infant Feeding in French Guiana

NCT ID: NCT06528275

Last Updated: 2024-07-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Total Enrollment

380 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-03-14

Study Completion Date

2026-08-31

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

This is a comparative, observal study among the population of pregant women who participated to the study "Nutri Pou Ti Moun" on food insecurity during pregnancy in French Guiana

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The international literature has already demonstrated the benefits of breastfeeding (BF) in the short, medium and long term for the health of children and mothers alike. For children, breastfeeding helps to reduce mortality from infections, prevents hospitalisations, particularly for gastroenteritis and respiratory illnesses, and prevents diabetes and childhood obesity. Breastfeeding also plays an important role in children's cognitive development, with an impact on IQ and academic success. For mothers, not breastfeeding is associated with an increased risk of breast and ovarian cancer, type II diabetes, obesity and cardiovascular disorders. Similarly, the WHO recommends optimal feeding practices for infants up to 2 years of age, i.e. early initiation of breastfeeding to allow the child to receive colostrum, exclusive BF for 4 to 6 months, and the timely introduction of liquid, semi-solid or solid foods, the continuation of BF for up to 2 years and beyond, the consumption of age-appropriate infant formula (IF) as an alternative to breastfeeding, and a minimum acceptable intake of complementary food to breast or infant milk.

On a national scale, the 'first 1000 days' initiative (from the 4th month of pregnancy to the child's 2nd birthday) that emerged at the symposium on 23 September 2021 organised by Santé Publique France and the French Ministry of Solidarity and Health includes the objective of promoting good BF practices. Similarly, the 2019-2023 national nutrition and health plan (PNNS4) aims to increase the percentage of children breastfed at birth by at least 15% and to extend the median duration of total breastfeeding by 2 weeks. In French Guyana, the 2023-2028 regional health plan points out that perinatal indicators in the French overseas territories are worse than in mainland France, and that improving mother and child health must involve improving the environment in which children live during their first 1,000 days.

In 2005, an initial retrospective study of breastfeeding practices was carried out in western part of French Guiana and showed a rate of exclusive breastfeeding at 4 months of age of 3% and a rate of continued breastfeeding of 16.7% up to 1 year and 6.5% up to 2 years. Between 2010 and 2012, a prospective survey of the whole of French Guiana found an exclusive BF rate of 27% at 1 month, 9% at 3 months and 5% at 6 months. In the Epifane survey conducted in France between 2010 and 2012, the rate of exclusive breastfeeding at 1 month and 3 months was close to that in French Guiana (28% and 10% respectively), with an average duration of exclusive or predominant breastfeeding of 3 weeks.

The rate of continued breastfeeding for up to 1 year was estimated at 16% in the Guiana study, compared with 9% in France. The rate of mixed breastfeeding concerned 30% of women breastfeeding from the maternity hospital in French Guiana, compared with 20% in France. The main reasons for introducing bottles of infant formula (IF) in both French Guiana and France were the impression of a lack of milk (the child's feeling of dissatisfaction) and the return to work. On the other hand, almost 1 in 2 women in French Guiana stated that no healthcare professional had shown any interest in their breastfeeding at 1 month post-partum.

Since January 2023, the Nutri Pou Ti'moun study ('Nutri 1 project' ID-RCB 2022-A01772-41), carried out in 3 maternity units in French Guiana and involving 800 women who have given birth - the 'Nutri 1 women's group' - aims to take stock of women's food insecurity during pregnancy and to describe the medical consequences observed on the course and outcome of pregnancy and on infant health in the immediate post-partum period. In the course of this project, the links between vitamin and mineral deficiencies, heavy metal impregnation and maternal dietary diversification are being studied. In the Guianese context of multidimensional precariousness, the Guianese perinat network, in partnership with local and institutional players, aimed to set up a health and nutrition pathway from the 4th month of pregnancy in October 2023, comprising weekly workshops co-hosted by a health mediator (on diet, well-being, adapted physical activities and the promotion of breastfeeding) and the distribution of baskets of fresh, local fruit and vegetables.

This health promotion intervention is offered to pregnant women attending the maternal and child health protection centre (PMI) in the Communauté d'agglomération du centre littoral (CACL) - the 'Nutri 2 women's group'. This intervention gave rise to an ancillary research project to the Nutri Pou Ti'moun research project, the Nutri pou ti'moun 2 project (Nutri 2 project; ID-RCB 2023-A00167-38) aimed at assessing the impact of this action on women's diet (diversity and food insecurity) by comparing the data from the Nutri 1 women's group with that from the Nutri 2 women's group. These projects only cover the period from pregnancy to the immediate post-partum period. By 31 December 2023, 786 women had been included in the Nutri 1 project and 57 women in the ancillary Nutri 2 project.

The relevance and interest of conducting research in French Guiana on breastfeeding practices and, more broadly, on infant feeding are justified:

* On the one hand, by the absence of recent published data on infant feeding practices in French Guiana. The second national Epifane survey, to be carried out in 2021 and focusing on infant nutrition during the first year of life, is a study being conducted in parallel with the national perinatal survey in France. An extension of this survey was carried out in the French overseas departments and territories, but French Guiana was not included.
* On the other hand, the Nutri Pou Ti Moun project represents an opportunity to collect data on infant feeding from a representative sample of women giving birth in French Guiana, in the three public maternity hospitals (Nutri 1 group of women). Medical, biomedical and socio-demographic data, as well as data relating to food safety and nutrition during pregnancy already collected during the Nutri Pou Ti moun project, will be analysed with regard to infant feeding practices and child development data (staturo-weight, cranial perimeter, psychomotor development). The impact of a prenatal intervention on nutrition could also be assessed by comparing infant feeding data for children in the Nutri 1 group and those in the Nutri 2 group.

In a socio-economic and health context that is different from that in mainland France, food insecurity in French Guiana during pregnancy, as assessed in the Nutri Pou Ti moun project, is likely to have consequences for young children that it would be relevant to measure and compare with national and international data. In the short term, the impact of this food insecurity would influence the use and duration of breastfeeding, the occurrence of anaemia in young children and dietary practices; and in the medium term, the child's staturo-weight development and cognitive development.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Food Insecurity Pregnancy Related

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Group 1 - control

Pregant women included in Nutri Pou Ti Moun 1 project who did not benefit from the health promotion intervention

No interventions assigned to this group

Group 2 - intervention

Pregant women included in Nutri Pou Ti Moun 1 project who benefited from the health promotion intervention

Health promotion intervention

Intervention Type OTHER

Health promotion intervention with activites linked to nutrition, and distribution of baskets of fresh fruits and vegetables

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Health promotion intervention

Health promotion intervention with activites linked to nutrition, and distribution of baskets of fresh fruits and vegetables

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Intervention group : women included in Nutri Pou Ti Moun project and who benefited from health promotion intervention
* Control group : women included in Nutri Pou Ti Moun project and who did not benefit from health promotion intervention

Exclusion Criteria

* Women refusing to participate to the study
* Women who moved out of French Guiana
* Women lost for follow up or who could not be contacted for the participation to the study
* Minor women who could not obtain authorisation from legal representatives
Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Centre Hospitalier de Cayenne

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Celia BASURKO, MD

Role: PRINCIPAL_INVESTIGATOR

Centre Hospitalier de Cayenne

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Centre Hospitalier de Cayenne

Cayenne, , French Guiana

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

French Guiana

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Celia BASURKO, MD

Role: CONTACT

+594 5 94 39 57 66

Mathieu NACHER, PhD

Role: CONTACT

+594 5 94 39 53 85

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Celia BASURKO, MD

Role: primary

+594 5 94 39 57 66

Mathieu NACHER, PhD

Role: backup

+594 5 94 39 53 85

References

Explore related publications, articles, or registry entries linked to this study.

Victora CG, Bahl R, Barros AJ, Franca GV, Horton S, Krasevec J, Murch S, Sankar MJ, Walker N, Rollins NC; Lancet Breastfeeding Series Group. Breastfeeding in the 21st century: epidemiology, mechanisms, and lifelong effect. Lancet. 2016 Jan 30;387(10017):475-90. doi: 10.1016/S0140-6736(15)01024-7.

Reference Type BACKGROUND
PMID: 26869575 (View on PubMed)

Sankar MJ, Sinha B, Chowdhury R, Bhandari N, Taneja S, Martines J, Bahl R. Optimal breastfeeding practices and infant and child mortality: a systematic review and meta-analysis. Acta Paediatr. 2015 Dec;104(467):3-13. doi: 10.1111/apa.13147.

Reference Type BACKGROUND
PMID: 26249674 (View on PubMed)

Horta BL, Loret de Mola C, Victora CG. Long-term consequences of breastfeeding on cholesterol, obesity, systolic blood pressure and type 2 diabetes: a systematic review and meta-analysis. Acta Paediatr. 2015 Dec;104(467):30-7. doi: 10.1111/apa.13133.

Reference Type BACKGROUND
PMID: 26192560 (View on PubMed)

Binns C, Lee M, Low WY. The Long-Term Public Health Benefits of Breastfeeding. Asia Pac J Public Health. 2016 Jan;28(1):7-14. doi: 10.1177/1010539515624964.

Reference Type BACKGROUND
PMID: 26792873 (View on PubMed)

Chowdhury R, Sinha B, Sankar MJ, Taneja S, Bhandari N, Rollins N, Bahl R, Martines J. Breastfeeding and maternal health outcomes: a systematic review and meta-analysis. Acta Paediatr. 2015 Dec;104(467):96-113. doi: 10.1111/apa.13102.

Reference Type BACKGROUND
PMID: 26172878 (View on PubMed)

Basurko C, Dupart O, Savy M, Obert-Marby C, Mvogo A, Gonzalez A, Trepont A, Cann L, Boceno C, Osei L, Creton PM, Dufit V, Thelusme L, Adenis A, Van-Melle A, Huber F, Nacher M. Hunger in French Guiana's Vulnerable Urban Neighborhoods: A Neglected Consequence of COVID-19. Food Nutr Bull. 2023 Mar;44(1):3-11. doi: 10.1177/03795721231156641. Epub 2023 Feb 23.

Reference Type BACKGROUND
PMID: 36824041 (View on PubMed)

Nacher M, Basurko C, Muhigirwa GB, Lambert V, Osei L, Njuieyon F, Louis A, Dotou D, Thomas N, Bernard S, Leneuve M, Elenga N, Hcini N. Infant mortality in French Guiana between 2001 and 2017 : Trends and comparisons with mainland France. Rev Epidemiol Sante Publique. 2023 Dec;71(6):102175. doi: 10.1016/j.respe.2023.102175. Epub 2023 Oct 31.

Reference Type BACKGROUND
PMID: 37918040 (View on PubMed)

Related Links

Access external resources that provide additional context or updates about the study.

https://iris.who.int/handle/10665/95585

Short-term effects of breastfeeding: a systematic review on the benefits of breastfeeding on diarrhoea and pneumonia mortality

https://iris.who.int/bitstream/handle/10665/43895/9789241596664_eng.pdf?sequence=1

Indicators for assessing infant and young child feeding practices

https://www.santepubliquefrance.fr/a-propos/evenements/colloque-les-1000-premiers-jours-23-septembre-2021

Conference on the "1000 first days" - Santé Publique France - 23 September 2021

https://sante.gouv.fr/IMG/pdf/pnns4_2019-2023.pdf

French national health and nutrition program

https://beh.santepubliquefrance.fr/beh/2014/27/2014_27_2.html

Duration of breastfeeding period in France - Epifane survey 2012-2013

https://www.guyane.ars.sante.fr/media/116268/download?inline

French Guiana Regional program on access to prevention and care

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

ANJE Nutri

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Uganda Birth Cohort Study
NCT04233944 TERMINATED
Nurturing Care Family Navigator
NCT06859372 RECRUITING NA
Oral Health and Pregnancy
NCT04992754 UNKNOWN
Ghana MHL Project, Tamale
NCT06898346 NOT_YET_RECRUITING NA
Text for Prenatal Health Study
NCT01951014 COMPLETED NA