A Study on Rare Dermatological Infections Conducted at Three Major Reference Hospitals in Costa Rica.

NCT ID: NCT06523998

Last Updated: 2024-07-29

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 95 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2023-12-11
• Study Completion Date: 2024-05-24

Brief Summary

In Costa Rica there are some descriptive studies of some of these rare infectious diseases (sporotrichosis, chromomycosis and mycetomas); however, there are no recent published reports. Most of the publications on the subject date back to the previous century; from 2000 to the present year there are only publications of small series of cases, so the current behavior of these skin infections is unknown. The primary objective is to analyze the epidemiological, clinical, and therapeutic profile and determine the risk factors in patients with a diagnosis of rare infections of dermatological interest treated at Hospital México, Hospital Rafael Calderón Guardia, and Hospital San Juan de Dios during the period 2019-2023.

Conditions

Sporotrichosis; Chromomycosis; Actinomycosis; Nocardiosis; Mycetoma; Mycobacterial Cutaneous Infection; Coccidioidomycosis; Blastomycosis; Paracoccidioidomycosis; Phaeomycosis

Study Design

• Observational Model Type: OTHER
• Study Time Perspective: RETROSPECTIVE

Eligibility Criteria

Inclusion Criteria

1. Age over 18 years, regardless of gender and ethnic group.

2. Patients who during the period from January 1, 2019 to December 31, 2023 received medical care at the Hospital Rafael Ángel Calderón Guardia, Hospital México and Hospital San Juan de Dios.

3. Subjects who meet a confirmed microbiological, histological and/or molecular diagnosis of sporotrichosis, chromomycosis, actinomycosis, nocardiosis, mycetoma, mycobacterial infection, coccidioidomycosis, blastomycosis, paracoccidioidomycosis, cutaneous nocardiosis and pheomycotic abscess (either through the unique digital health record, pathology registries, clinical laboratory service database of each hospital, clinical laboratory of the University of Costa Rica and Instituto Costarricense de Investigación y Enseñanza en Nutrición y Salud).

4. Subjects diagnosed at a private level and referred to continue medical care at Hospital Rafael Ángel Calderón Guardia, Hospital México and Hospital San Juan de Dios.

Exclusion Criteria

1. The research team may exclude patients who have an unconfirmed diagnosis, an erroneous diagnosis, or have participated in the study before, as they may hinder the ability to obtain satisfactory data to achieve the study's objectives.

2. Patients who have more than 30% of the variables required for analysis missing will also be excluded from the study.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 120 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Caja Costarricense de Seguro Social

OTHER_GOV

Sponsor Role: lead

Responsible Party

Daniel Barquero Orias

Medical Doctor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Daniel E Barquero Orias, MD

Role: PRINCIPAL_INVESTIGATOR

Caja Costarricense de Seguro Social

Locations

Hospital Rafael Ángel Calderón Guardia

San José, , Costa Rica

Hospital San Juan de Dios

San José, , Costa Rica

Hospital México

San José, , Costa Rica

Countries

Costa Rica

References

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Other Identifiers

R023-SABI-00344

Identifier Type: -

Identifier Source: org_study_id