Effect of Biologic Therapy on Surgical Outcomes for Perforated Crohn's Patients

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2015-07-09

Study Completion Date

2025-07-09

Brief Summary

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crohn's disease patients who present by intestinal perforation as the first presentation are hard to deal with. Surgical techniques as anastmosis or diversion stoma and active course of the disease may greatly affect the quality of life. In post-operative period, is the priority to avoid the post operative complications and to improve surgical outcomes or to stop active course of the disease and to induce remission?. So, those patients were classified into two groups. one group received biological therapy early post operative and the other group received it 2 or 3 months later after surgery and the investigators will compare results between the two groups.

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Detailed Description

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Conditions

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Crohn Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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post operative Crohn's patients

early biologic therapy

Intervention Type BIOLOGICAL

biologic therapy for perforated Crohn's disease in the early postoperative period

post operative Cronn's patients

late biologic therapy

Intervention Type BIOLOGICAL

no biologic therapy for perforated Crohn's disease up to 2 to3 months in the post operative period

Interventions

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early biologic therapy

biologic therapy for perforated Crohn's disease in the early postoperative period

Intervention Type BIOLOGICAL

late biologic therapy

no biologic therapy for perforated Crohn's disease up to 2 to3 months in the post operative period

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

* patients at or above 18 years old
* patients with perforated bowel diagnosed as Crohn's disease at presentation underwent surgery

Exclusion Criteria

* patients less than 18 years old
* well known Crohn's disease patients on medical treatment
* associated bowel disease as malignancy and diverticulosis.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No