Clinical and Instrumental Assessment of Meniscal ROOT Tears Treated Through Suture to the Posterior Cruciate Ligament

NCT ID: NCT06507241

Last Updated: 2025-11-19

Basic Information

• Recruitment Status: RECRUITING
• Total Enrollment: 59 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2024-10-18
• Study Completion Date: 2027-12-31

Brief Summary

The menisci are crucial for knee stability and functionality. Composed of fibrocartilaginous structure, they have an anatomical and biomechanical arrangement that makes them essential for load transmission and the prevention of osteoarthritis. Meniscal root lesions, known as "ROOT tears," compromise their protective function on the cartilage, leading to increased contact pressures between the tibia and femur and, over time, the development of osteoarthritis. Early diagnosis of these lesions is difficult and often the first detection is incidental. The subsequent challenges are significant due to a lack of pre-operative planning. A possible solution is a surgical technique involving arthroscopic suture of the posterior meniscal root along with the posterior cruciate ligament. This procedure does not require pre-operative planning and is applicable even in cases of incidental diagnosis.

Conditions

Meniscus Tear; Meniscus Lesion; Knee Injuries

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: OTHER

Eligibility Criteria

Inclusion Criteria

1. Age between 18 and 50 years at the time of surgery;

2. Male and female gender;

3. Patients undergoing surgical treatment for at least one year for "ROOT" type meniscal lesions using arthroscopic suturing to the posterior cruciate ligament;

4. Pre-operative MRI performed.

Exclusion Criteria

1. Patients no longer reachable;

2. Patients who refuse consent to the study;

3. Previous meniscectomy before surgery;

4. Previous ligament injuries before surgery;

5. New traumatic injuries after surgery;

6. Advanced knee osteoarthritis (Outerbridge grade III-IV) at the time of surgery;

7. Severe knee malalignment (> 5°) at the time of surgery;

8. Severe obesity (BMI > 35);

9. Lower limb conditions preventing full weight-bearing during evaluation;

10. Infection or hematological/rheumatic conditions at the time of evaluation.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 50 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Istituto Ortopedico Rizzoli

OTHER

Sponsor Role: lead

Responsible Party

Stefano Zaffagnini

Full Professor Medicine and Surgery, University of Bologna

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

IRCCS Istituto Ortopedico Rizzoli

Bologna, , Italy

Site Status: RECRUITING

Countries

Italy

Central Contacts

Stefano Zaffagnini

Role: CONTACT

stefano.zaffagnini@ior.it

0516366075

Facility Contacts

Stefano Zaffagnini

Role: primary

stefano.zaffagnini@ior.it

0516366075

Other Identifiers

ROOT-PCL

Identifier Type: -

Identifier Source: org_study_id