Early Diagnosis of Acute Renal Failure by Urine Trehalase Levels.

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

40 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-07-15

Study Completion Date

2024-09-15

Brief Summary

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We think that in surgical patients requiring hypotensive anesthesia, acute kidney injury, which may occur due to intraoperative renal hypoperfusion, can be diagnosed early by evaluating the urine trehalase value using the ELISA method, and thus, early diagnosed acute renal failure can be treated quickly and patients can be protected from subsequent complications in the postoperative period.

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Detailed Description

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Conditions

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Trehalase Levels Acute Kidney Injury

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Interventions

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trehalase levels

We think that in surgical patients requiring hypotensive anesthesia, acute kidney injury, which may occur due to intraoperative renal hypoperfusion, can be diagnosed early by evaluating the urine trehalase value using the ELISA method

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Being over the age of 18 and under the age of 65
* Having signed the BGOF form to be included in the study,
* Being in ASA 1 or ASA 2 classification
* Not having kidney failure or kidney disease
* No history of single kidney or renal transplantation
* Not using nephrotoxic drugs or agents before surgery
* Renal function tests taken preoperatively should be within normal ranges.
* No urinary tract infection or urinary problems (such as polyuria, oliguria or anuria)

Exclusion Criteria

* Those under the age of 18 or over the age of 65
* Those who do not want to participate in the study
* ASA 3 and above
* Having previously received treatment for kidney disease - including kidney stones -
* Having been previously diagnosed with acute or chronic renal failure
* Having a single kidney or a history of renal transplantation
* Using nephrotoxic drugs or agents (such as contrast material) before surgery
* Kidney function tests taken preoperatively are not within normal ranges
* Having a urinary tract infection or urinary problem (such as polyuria, oliguria or anuria)
* Having a history of kidney stones, acute renal failure or chronic renal failure
* Those with active infection or disease before surgery
* They were determined as patients for whom consent was not obtained for the study.

Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No