The Role of Breastmilk and Serum Exosomes in Neonatal Jaundice Due to ABO Incompatibility
NCT ID: NCT06502847
Last Updated: 2025-07-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
COMPLETED
338 participants
OBSERVATIONAL
2020-07-01
2023-06-01
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Autologous Cord Blood Infusion for the Prevention and Treatment of Prematurity Complications In Preterm Neonates
NCT02050971
Modified Diagnosis and Treatment of Neonatal Hemolysis With ETCOc in sNH
NCT06832800
Withholding Feeds During Red Blood Cell Transfusion and TRAGI
NCT02132819
Impact of Enteral Feeding on Splanchnic Oxygenation During Packed Red Blood Cell Transfusion in Preterm Infants
NCT06632314
Continuous Versus Intermittent Phototherapy in Treatment of Neonatal Jaundice
NCT06386731
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
CASE_CONTROL
PROSPECTIVE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Case ABO1
Newborns who receive treatment due to the ABO Incompability will be included in this group.
Exosome profile study
Neonatal serum and maternal exosome profiles will be studied in all groups.
Case ABO2
Newborns who have the ABO Incompability, but do not require treatment will be included in this group.
Exosome profile study
Neonatal serum and maternal exosome profiles will be studied in all groups.
Control
Healthy newborns without any disease or health condition will be included in this group
Exosome profile study
Neonatal serum and maternal exosome profiles will be studied in all groups.
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Exosome profile study
Neonatal serum and maternal exosome profiles will be studied in all groups.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* Newborns who are admitted to the study center due to ABO hemolytic disease
* Newborns with ABO incompatibility
* Healthy newborns
* Healthy mothers
Exclusion Criteria
* Congenital abnormalities
* Maternal Liver diseases
* Neonatal liver diseases
* Sepsis
* Neonatal jaundice due to the causes other than ABO incompatibility
* Acute or chronic disease state in newborn
* Maternal acute or chronic disease
* Medication or substance use effecting liver functions
28 Days
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Kanuni Sultan Suleyman Training and Research Hospital
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Seda Yilmaz Semerci
Assoc Prof
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
University of Health Sciences Istanbul KSS Training and Research Hospital
Istanbul, Kucukcekmece, Turkey (Türkiye)
Countries
Review the countries where the study has at least one active or historical site.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
43057
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.