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Study of Intra- and Interpersonal Multimodal Synchronizations in a Social Interaction in Individuals with a Diagnosis of Schizophrenia.

NCT ID: NCT06484387

Last Updated: 2024-12-09

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-11-08

Study Completion Date

2025-11-08

Brief Summary

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The aim of this study is to precisely identify deficits in intra- and interpersonal multimodal synchronizations during social interaction in individuals with schizophrenia (ISZ). During a social interaction, individuals use both visual and auditory channels to construct their discourse. The auditory channel encompasses the semantics and prosody of the speech, while the visual channel describes the entirety of non-verbal gestures (e.g., facial expressions, body movements). Prosody and non-verbal gestures are essential elements for the speaker. By accompanying speech, they contribute to the planning and conceptualization of the utterance and enhance its communicative power. For the listener, prosody and non-verbal gestures are also used to provide sensory feedback to the speaker.

Several studies have shown the existence of intrapersonal and interpersonal synchronizations of prosody and non-verbal gestures during interaction. These synchronizations are associated with numerous social benefits (e.g., increased mutual appreciation and quality of interaction). However, certain mental disorders, such as schizophrenia, exhibit deficits in non-verbal behaviors that can impair these synchronizations and the associated social benefits. We hypothetized that interaction with individuals with a daignosis of schizophrenia will be associated with deficits in intra and interpersonal synchronization.

Detailed Description

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This study includes a pre-inclusion interview followed by a visit to the university hospital (CHU) lasting about 2 hours (including a break). During the visit, the patient participates in an experimental protocol consisting of two parts. In the first part, the patient will be paired with an interaction partner, and the two participants will engage in four distinct conversational tasks, including getting to know each other, free discussions, structured dialogues, and emotional interactions. In the second part, the participants will answer several questionnaires and perform neuropsychological tests in collaboration with an experimenter

Conditions

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Schizophrenia

Keywords

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social interaction interpersonal synchronization

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

SINGLE

Participants

Study Groups

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dyad schizophrenia and interacting partner

social interaction between an individual with a diagnosis of schizophrenia and his interacting partner

Group Type EXPERIMENTAL

Social interaction

Intervention Type BEHAVIORAL

Participants are required to speak to one another. Participants are given various topics of conversation.

dyad healthy subject and interacting partner

social interaction between a healthy subject and his interacting partner

Group Type EXPERIMENTAL

Social interaction

Intervention Type BEHAVIORAL

Participants are required to speak to one another. Participants are given various topics of conversation.

Interventions

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Social interaction

Participants are required to speak to one another. Participants are given various topics of conversation.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* diagnosis of schizophrenia according to the DSM-V
* being able to read, speak and understand french
* giving eclaired consent


* being able to read, speak and understand french
* giving eclaired consent

Exclusion Criteria

* history of head trauma
* history of neurological conditions (epilespsy, multiple sclerosis, parkinson's disease, amyotrophic lateral sclerosis, huntington's disease, stroke)
* substance use
* pregnant women

Healthy controls :


* diagnosis of psychosis
* history of head trauma
* history of neurological conditions (epilespsy, multiple sclerosis, parkinson's disease, amyotrophic lateral sclerosis, huntington's disease, stroke)
* substance use
* pregnant women
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Euromov Digital Health in Motion

UNKNOWN

Sponsor Role collaborator

University Hospital, Montpellier

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Montpellier University Hospital

Montpellier, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Delphine Capdevielle, Pr

Role: CONTACT

Phone: 0467339702

Email: [email protected]

Mathilde Parisi

Role: CONTACT

Phone: 0632935910

Email: [email protected]

Facility Contacts

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Mathilde Parisi

Role: primary

Delphine CAPDEVIELLE

Role: backup

Other Identifiers

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RECHMPL22_0408

Identifier Type: -

Identifier Source: org_study_id