Causes, Characteristics and Treatment of Hypercalcemia in the Emergency Room of a German Hospital

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2010-01-01

Study Completion Date

2025-12-31

Brief Summary

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Patients with hypercalcemia were identified in the patient population of a German emergency department during a 11 year time period and studied regarding reproducibility of elevated calcium values, causes of hypercalcemia, symptoms. acute renal injury, mortality and treatment response.

Detailed Description

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Patients, who presented to the emergency department of a tertiary German hospital with a total calcium of ≥2.65 mmol/l between January 2010 and March 2021, was retrospectively studied. From the electronic patient records we analyzed if the elevated calcium values were reproducible in follow-up measurements, identified the cause of hypercalcemia, listed the symptoms, investigated a correlation between calcium and creatinine values to study acute renal injury directly due to hypercalcemia, calculated the mortality rate stratified by the calcium value on presentation and studied the treatment response regarding lowering calcium values by different treatments.

Conditions

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Hypercalcemia

Keywords

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hypercalcemia calcium emergency room mortality

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Retrospective Chart Review

Group includes patient with hypercalcemia ≥2.65 mmol/l, who reported to the emergency room of a tertiary hospital

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Age \> 18 years
* Total calcium ≥ 2.65 mmol/l
* Female and male

Exclusion Criteria

* Age \< 18 years
* Total calcium \< 2.65 mmol/

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Volker Burst

Prof. Dr. med.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Volker Burst, MD

Role: PRINCIPAL_INVESTIGATOR

University Hospital of Cologne

Locations

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Department II of Internal Medicine,University of Cologne

Cologne, , Germany

Site Status

Countries

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Germany

Other Identifiers

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V1.0-13.05.2024

Identifier Type: -

Identifier Source: org_study_id