3D Structural Imaging of Human Breast Tissues

NCT ID: NCT06454214

Last Updated: 2024-06-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-07-01

Study Completion Date

2027-06-04

Brief Summary

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This project aims to develop an advanced ex vivo medical microscopic imaging technology. By developing breast tissue staining techniques, acquiring microscopic images, and performing structural reconstruction, we seek to observe the 3D structure of breast tissue. This includes examining cell distribution, mammary ducts, and blood vessel distribution, to explore the different biological characteristics between normal breast tissue and various types of cancerous tissues.

Detailed Description

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Conditions

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Human Breast Tissues

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Control breast tissues (normal breast tissues)

Normal tissue contained within the surgically excised specimen

Multi-photon microscopy

Intervention Type DEVICE

To conduct 3D structural imaging on human breast tissues

Cancerous breast tissues

Tumor tissue contained within the surgically excised specimen

Multi-photon microscopy

Intervention Type DEVICE

To conduct 3D structural imaging on human breast tissues

Interventions

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Multi-photon microscopy

To conduct 3D structural imaging on human breast tissues

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Adults aged 18 and above.
* Patients clinically diagnosed with breast cancer.

Exclusion Criteria

* Patients unable to provide consent (e.g., inability to speak, inability to communicate in Chinese, etc.).
* Patients for whom a definitive pathological diagnosis cannot be established.
* Patients suitable only for biopsy and not for surgical excision.
* Excised tissue showing severe radiation-induced changes under pathological examination.
* Tumor specimens smaller than 1 cm.
* Patients with ductal carcinoma in situ (DCIS).
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Taiwan University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Central Contacts

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Ming-Yang Wang, PhD

Role: CONTACT

+886-23123456 ext. 263155

Yao-Chen Tseng, Master

Role: CONTACT

+886-33661552

Other Identifiers

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202405097RINB

Identifier Type: -

Identifier Source: org_study_id

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