OB-GYN Clinical Validation Study

NCT ID: NCT06449872

Last Updated: 2024-06-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

44 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-10-24

Study Completion Date

2024-04-30

Brief Summary

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This is a single-site study evaluating obstetrics and gynecology exam imaging quality by expert users.

Detailed Description

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Six healthcare professionals with training and experience in Obstetrics and Gynecology ultrasound qualitatively assessed the image quality of the Kosmos Diagnostic Ultrasound System compared to the benchmark Mindray M9 Ultrasound System. Five sonographers were required to complete each scanning cohort of at least three gravid and three non-gravid participants. A sixth sonographer was added to the study to accommodate a scheduling conflict and provided additional image quality data outside of the five completed cohorts.

The following views/structures were assessed for image quality:

Gynecology participants:

* Uterus
* Ovaries
* Endometrial cavity
* Cervix

• Obstetrics participants in their 1st trimester:
* General image quality of the fetus
* Ability to visualize the crown rump length
* Visualization of gestational sac
* Visualization of yolk sac if present

• Obstetrics and participants in their 2nd trimester:
* General image quality of the fetal structures
* Visualization of the amniotic fluid
* Visualization of the placenta
* Cardiac motion in 2D and M-mode with heart rate

Obstetrics and participants in their 3rd trimester:

* General image quality of the fetal structures
* Visualization of the amniotic fluid
* Visualization of the placenta
* Visualization of the maternal cervix
* Cardiac motion in 2D and M-mode with heart rate
* 3 vessel umbilical cord in 2D and Color Doppler The sonographers captured all views/structures on the Mindray M9 Ultrasound System, then switched over to the Kosmos Diagnostic Ultrasound System to capture the same views/structures. Once all views/structures were captured on both ultrasound systems, the healthcare professionals reviewed the images in parallel on each system, then provided a comparison score for Kosmos between 1 and 7.

Conditions

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Obstetric Complication GYN Disorders

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Comparison scanning protocol for OB and GYN clinical applications

Image quality comparative assessment

Group Type OTHER

Obstetrics and Gynecology clinical applications for ultrasound diagnostic systems

Intervention Type DEVICE

Up to 5 healthcare professionals trained and experienced in Obstetrics and Gynaecology ultrasound qualitatively assessed the diagnostic image quality of the Kosmos Diagnostic Ultrasound System against the benchmark Mindray M9 Ultrasound System.

Interventions

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Obstetrics and Gynecology clinical applications for ultrasound diagnostic systems

Up to 5 healthcare professionals trained and experienced in Obstetrics and Gynaecology ultrasound qualitatively assessed the diagnostic image quality of the Kosmos Diagnostic Ultrasound System against the benchmark Mindray M9 Ultrasound System.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

1. Persons able to:

1. Read and sign an English consent form.
2. Read and complete an English demographic and general health survey.
3. Give consent for participation.
4. Able and willing to comply with study requirements.
2. Those aged 18 years through 40 years, healthy, particularly in respect to their pregnancy.
3. Pregnant individuals who have received a previous ultrasound exam by their physician.

Exclusion Criteria

1. Children (minors) under 18 years old.
2. Adults over 40 years old.
3. Those who cannot or refuse to sign their consent.
4. Those who cannot provide informed consent.
5. Vulnerable populations, i.e., individuals whose willingness to participate in the study could be unduly influenced by the expectation of medical benefits associated with participation.
6. Vulnerable populations, i.e., individuals whose willingness to participate in the study could be unduly influenced by parents, employer or monetary benefit.
7. Pregnant individuals who have not received a previous ultrasound exam by their physician.
8. Individuals who have had a hysterectomy, oophorectomy, and trachelectomy.
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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EchoNous Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Robert Blankenship, MD

Role: PRINCIPAL_INVESTIGATOR

Mercy West Hospital

Locations

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EchoNous, Inc.

Redmond, Washington, United States

Site Status

Countries

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United States

Other Identifiers

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ECHO-007

Identifier Type: -

Identifier Source: org_study_id

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