Bicentric Clinical Investigation to Assess Safety and Performance of LuxHighAdd IOL

NCT ID: NCT06446817

Last Updated: 2025-02-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

57 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-12-19

Study Completion Date

2026-07-01

Brief Summary

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The study purpose is to demonstrate safety and performance of bilateral implantation of LuxHighAdd intraocular lens compared with the LuxGood Monofocal lens.

Detailed Description

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The study purpose is to demonstrate safety and performance after bilateral implantation of LuxHighAdd intraocular lenses.

The device under investigation is a hydrophobic acrylic multifocal intraocular lens (IOL) manufactured by the sponsor of this study.

Conditions

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Cataract

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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LuxHighAdd

The experimental group will recieve the LuxHighAdd intraocular lens bilaterally.

Group Type EXPERIMENTAL

LuxHighAdd IOL

Intervention Type DEVICE

Bilateral implantation in the capsular bag to replace the cataractous human crystalline lens.

LuxGood group

The control group will recieve the LuxGood intraocular lens bilaterally.

Group Type ACTIVE_COMPARATOR

LuxGood IOL

Intervention Type DEVICE

Bilateral implantation in the capsular bag to replace the cataractous human crystalline lens.

Interventions

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LuxHighAdd IOL

Bilateral implantation in the capsular bag to replace the cataractous human crystalline lens.

Intervention Type DEVICE

LuxGood IOL

Bilateral implantation in the capsular bag to replace the cataractous human crystalline lens.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Subject aged 50 or over on the day of inclusion, presenting a bilateral cataract, qualified for bilateral implantation
* No ocular comorbidity possibly affecting the study results
* Fit within the available IOL diopter range
* Have had no previous refractive surgery
* Regular corneal astigmatism ≤1.0 dioptres
* Clear intraocular media other than cataract
* Availability, willingness and sufficient cognitive awareness to comply with examination procedures
* Ability to attend all study follow-ups
* Signed informed consent.

Exclusion Criteria

* Ocular surface disease potentially affecting study results
* Pre-existing ocular pathology or history of pathology potentially affecting the study results
* Acute or chronic disease or illness that would increase risk or confound study results
* Subjects who may be reasonably expected to require a secondary surgical intervention at any time during the investigation (other than YAG capsulotomy)
* Axial lengths and keratometry such as the IOL spherical power is not in the range of 16 to 26 D
* Instability of keratometry or biometry measurements
* Traumatic cataract
* Amblyopia
* History of ocular trauma or any prior ocular surgery including refractive procedures
* Capsular or zonular abnormalities that may affect postoperative centration or tilt of the lens
* Pupil abnormalities
* Systemic or ocular medication that could modify pupil dynamics
* Expected complicated surgery or complicated surgery
* Concurrent participation in another drug or device investigation
Minimum Eligible Age

50 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cutting Edge SAS

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Alain Saad, MD

Role: PRINCIPAL_INVESTIGATOR

Hôpital Fondation Adolphe de Rothschild

Locations

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Hôpital Fondation Adolphe de Rothschild

Paris, , France

Site Status RECRUITING

WestOphta

Rennes, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Line Bettinelli, OD

Role: CONTACT

0619530701

Christophe Cesses

Role: CONTACT

0786991458

Facility Contacts

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Alain Saad, MD

Role: primary

Pierre-Emmanuel Arcade, MD

Role: primary

Other Identifiers

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2023-A01904-41

Identifier Type: REGISTRY

Identifier Source: secondary_id

CE2301

Identifier Type: -

Identifier Source: org_study_id

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