Trial Outcomes & Findings for Impacts of Alcohol Warning Labels: An Online Experiment (NCT NCT06442800)
NCT ID: NCT06442800
Last Updated: 2025-08-15
Results Overview
The study will assess perceived message effectiveness using 1 item: "How much does this message make you want to drink less alcohol?" Response options will range from "not at all" (coded as 1) to "a great deal" (coded as 5). Higher scores indicate more perceived message effectiveness. Survey weighted means are reported to account for NORC AmeriSpeak's sampling design to enable results to be statistically representative of the US population of drinkers age \>/=21 who drink alcohol.
Recruitment status
COMPLETED
Study phase
NA
Target enrollment
1123 participants
Primary outcome timeframe
Assessed during one-time 15-minute online study survey
Results posted on
2025-08-15
Participant Flow
Participant milestones
| Measure |
Alcohol Messages
Participants will view and rate 10 messages shown on alcohol containers.
Liver Cancer: Participants will view messages about the risk of liver cancer from alcohol consumption.
Throat and Mouth Cancer: Participants will view messages about the risk of throat and mouth cancer from alcohol consumption.
Colorectal Cancer: Participants will view messages about the risk of colorectal cancer from alcohol consumption.
Multiple Cancers: Participants will view messages about the risk of multiple cancers from alcohol consumption.
Liver Disease: Participants will view messages about the risk of liver disease from alcohol consumption.
Hypertension: Participants will view messages about the risk of hypertension from alcohol consumption.
Dementia: Participants will view messages about the risk of dementia from alcohol consumption.
Drinking Guidelines: Participants will view messages about guidelines for alcohol consumption.
Current Warning: Participants will view the current warning that is required on most alcoholic beverage containers sold in the US.
Control: Participants will view neutral messages unrelated to the harms of alcohol consumption.
|
|---|---|
|
Overall Study
STARTED
|
1123
|
|
Overall Study
Completed >/= 90% of Survey
|
1087
|
|
Overall Study
Completed Survey in Realistic Timeframe
|
1036
|
|
Overall Study
COMPLETED
|
1036
|
|
Overall Study
NOT COMPLETED
|
87
|
Reasons for withdrawal
Withdrawal data not reported
Baseline Characteristics
Impacts of Alcohol Warning Labels: An Online Experiment
Baseline characteristics by cohort
| Measure |
Alcohol Messages
n=1036 Participants
Participants will view and rate 10 messages shown on alcohol containers.
Liver Cancer: Participants will view messages about the risk of liver cancer from alcohol consumption.
Throat and Mouth Cancer: Participants will view messages about the risk of throat and mouth cancer from alcohol consumption.
Colorectal Cancer: Participants will view messages about the risk of colorectal cancer from alcohol consumption.
Multiple Cancers: Participants will view messages about the risk of multiple cancers from alcohol consumption.
Liver Disease: Participants will view messages about the risk of liver disease from alcohol consumption.
Hypertension: Participants will view messages about the risk of hypertension from alcohol consumption.
Dementia: Participants will view messages about the risk of dementia from alcohol consumption.
Drinking Guidelines: Participants will view messages about guidelines for alcohol consumption.
Current Warning: Participants will view the current warning that is required on most alcoholic beverage containers sold in the US.
Control: Participants will view neutral messages unrelated to the harms of alcohol consumption.
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|---|---|
|
Age, Customized
21-29 years
|
115 Participants
n=5 Participants
|
|
Age, Customized
30-44 years
|
342 Participants
n=5 Participants
|
|
Age, Customized
45-59 years
|
247 Participants
n=5 Participants
|
|
Age, Customized
60 years or older
|
332 Participants
n=5 Participants
|
|
Sex/Gender, Customized
Woman
|
509 Participants
n=5 Participants
|
|
Sex/Gender, Customized
Man
|
524 Participants
n=5 Participants
|
|
Sex/Gender, Customized
Non-Binary or another gender
|
3 Participants
n=5 Participants
|
|
Race/Ethnicity, Customized
American Indian or Alaska Native
|
10 Participants
n=5 Participants
|
|
Race/Ethnicity, Customized
Asian
|
39 Participants
n=5 Participants
|
|
Race/Ethnicity, Customized
Black or African American
|
115 Participants
n=5 Participants
|
|
Race/Ethnicity, Customized
Hispanic, Latino, or Spanish
|
138 Participants
n=5 Participants
|
|
Race/Ethnicity, Customized
Middle Eastern or North African
|
2 Participants
n=5 Participants
|
|
Race/Ethnicity, Customized
Native Hawaiian or other Pacific Islander
|
1 Participants
n=5 Participants
|
|
Race/Ethnicity, Customized
White
|
681 Participants
n=5 Participants
|
|
Race/Ethnicity, Customized
Another race or ethnicity
|
8 Participants
n=5 Participants
|
|
Race/Ethnicity, Customized
More than one race or ethnicity
|
32 Participants
n=5 Participants
|
|
Race/Ethnicity, Customized
Unknown/Did not report race or ethnicity
|
10 Participants
n=5 Participants
|
|
Region of Enrollment
United States
|
1036 Participants
n=5 Participants
|
PRIMARY outcome
Timeframe: Assessed during one-time 15-minute online study surveyPopulation: This study compares the message effectiveness of the topic message to the control message. Messages within each topic were not compared to one another.
The study will assess perceived message effectiveness using 1 item: "How much does this message make you want to drink less alcohol?" Response options will range from "not at all" (coded as 1) to "a great deal" (coded as 5). Higher scores indicate more perceived message effectiveness. Survey weighted means are reported to account for NORC AmeriSpeak's sampling design to enable results to be statistically representative of the US population of drinkers age \>/=21 who drink alcohol.
Outcome measures
| Measure |
Alcohol Messages
n=1036 Participants
Participants will view and rate 10 messages shown on alcohol containers.
Liver Cancer: Participants will view messages about the risk of liver cancer from alcohol consumption.
Throat and Mouth Cancer: Participants will view messages about the risk of throat and mouth cancer from alcohol consumption.
Colorectal Cancer: Participants will view messages about the risk of colorectal cancer from alcohol consumption.
Multiple Cancers: Participants will view messages about the risk of multiple cancers from alcohol consumption.
Liver Disease: Participants will view messages about the risk of liver disease from alcohol consumption.
Hypertension: Participants will view messages about the risk of hypertension from alcohol consumption.
Dementia: Participants will view messages about the risk of dementia from alcohol consumption.
Drinking Guidelines: Participants will view messages about guidelines for alcohol consumption.
Current Warning: Participants will view the current warning that is required on most alcoholic beverage containers sold in the US.
Control: Participants will view neutral messages unrelated to the harms of alcohol consumption.
|
|---|---|
|
Perceived Message Effectiveness
Multiple cancers
|
2.66 score on a scale
Standard Error 0.05
|
|
Perceived Message Effectiveness
Dementia
|
2.54 score on a scale
Standard Error 0.05
|
|
Perceived Message Effectiveness
Colorectal cancer
|
2.52 score on a scale
Standard Error 0.05
|
|
Perceived Message Effectiveness
Liver cancer
|
2.50 score on a scale
Standard Error 0.05
|
|
Perceived Message Effectiveness
Throat and mouth cancer
|
2.49 score on a scale
Standard Error 0.05
|
|
Perceived Message Effectiveness
Liver disease
|
2.46 score on a scale
Standard Error 0.05
|
|
Perceived Message Effectiveness
Hypertension
|
2.33 score on a scale
Standard Error 0.05
|
|
Perceived Message Effectiveness
Current warning
|
2.15 score on a scale
Standard Error 0.05
|
|
Perceived Message Effectiveness
Guidelines
|
1.93 score on a scale
Standard Error 0.05
|
|
Perceived Message Effectiveness
Control
|
1.35 score on a scale
Standard Error 0.04
|
SECONDARY outcome
Timeframe: Assessed during one-time 15-minute online study surveyThe study will assess reminding of alcohol's harms using 1 item: "How much does this message remind you that drinking alcohol can be harmful?" Response options will range from not at all (1) to a great deal (5). Higher scores indicate greater reminding of alcohol's harms. Survey weighted means are reported to account for NORC AmeriSpeak's sampling design to enable results to be statistically representative of the US population of drinkers age \>/=21 who drink alcohol.
Outcome measures
| Measure |
Alcohol Messages
n=1036 Participants
Participants will view and rate 10 messages shown on alcohol containers.
Liver Cancer: Participants will view messages about the risk of liver cancer from alcohol consumption.
Throat and Mouth Cancer: Participants will view messages about the risk of throat and mouth cancer from alcohol consumption.
Colorectal Cancer: Participants will view messages about the risk of colorectal cancer from alcohol consumption.
Multiple Cancers: Participants will view messages about the risk of multiple cancers from alcohol consumption.
Liver Disease: Participants will view messages about the risk of liver disease from alcohol consumption.
Hypertension: Participants will view messages about the risk of hypertension from alcohol consumption.
Dementia: Participants will view messages about the risk of dementia from alcohol consumption.
Drinking Guidelines: Participants will view messages about guidelines for alcohol consumption.
Current Warning: Participants will view the current warning that is required on most alcoholic beverage containers sold in the US.
Control: Participants will view neutral messages unrelated to the harms of alcohol consumption.
|
|---|---|
|
Reminding of Alcohol's Harms
Multiple cancers
|
3.15 score on a scale
Standard Error 0.05
|
|
Reminding of Alcohol's Harms
Dementia
|
2.99 score on a scale
Standard Error 0.05
|
|
Reminding of Alcohol's Harms
Colorectal cancer
|
2.93 score on a scale
Standard Error 0.05
|
|
Reminding of Alcohol's Harms
Liver cancer
|
3.00 score on a scale
Standard Error 0.05
|
|
Reminding of Alcohol's Harms
Throat and mouth cancer
|
3.06 score on a scale
Standard Error 0.05
|
|
Reminding of Alcohol's Harms
Liver disease
|
2.92 score on a scale
Standard Error 0.05
|
|
Reminding of Alcohol's Harms
Hypertension
|
2.84 score on a scale
Standard Error 0.05
|
|
Reminding of Alcohol's Harms
Current warning
|
2.91 score on a scale
Standard Error 0.05
|
|
Reminding of Alcohol's Harms
Guidelines
|
2.33 score on a scale
Standard Error 0.05
|
|
Reminding of Alcohol's Harms
Control
|
1.40 score on a scale
Standard Error 0.04
|
SECONDARY outcome
Timeframe: Assessed during one-time 15-minute online study surveyThe study will assess learning something new with 1 item: "Did you learn something new from this message?" Response options will be yes (1) and no (0). Proportion of participants who endorsed learning something new (i.e., answered 1). Survey weighted proportions are reported to account for NORC AmeriSpeak's sampling design to enable results to be statistically representative of the US population of drinkers age \>/=21 who drink alcohol.
Outcome measures
| Measure |
Alcohol Messages
n=1036 Participants
Participants will view and rate 10 messages shown on alcohol containers.
Liver Cancer: Participants will view messages about the risk of liver cancer from alcohol consumption.
Throat and Mouth Cancer: Participants will view messages about the risk of throat and mouth cancer from alcohol consumption.
Colorectal Cancer: Participants will view messages about the risk of colorectal cancer from alcohol consumption.
Multiple Cancers: Participants will view messages about the risk of multiple cancers from alcohol consumption.
Liver Disease: Participants will view messages about the risk of liver disease from alcohol consumption.
Hypertension: Participants will view messages about the risk of hypertension from alcohol consumption.
Dementia: Participants will view messages about the risk of dementia from alcohol consumption.
Drinking Guidelines: Participants will view messages about guidelines for alcohol consumption.
Current Warning: Participants will view the current warning that is required on most alcoholic beverage containers sold in the US.
Control: Participants will view neutral messages unrelated to the harms of alcohol consumption.
|
|---|---|
|
Learning Something New
Multiple cancers
|
0.52 proportion of positive responses
|
|
Learning Something New
Dementia
|
0.48 proportion of positive responses
|
|
Learning Something New
Colorectal cancer
|
0.54 proportion of positive responses
|
|
Learning Something New
Liver cancer
|
0.28 proportion of positive responses
|
|
Learning Something New
Throat and mouth cancer
|
0.51 proportion of positive responses
|
|
Learning Something New
Liver disease
|
0.25 proportion of positive responses
|
|
Learning Something New
Hypertension
|
0.39 proportion of positive responses
|
|
Learning Something New
Current warning
|
0.18 proportion of positive responses
|
|
Learning Something New
Guidelines
|
0.28 proportion of positive responses
|
|
Learning Something New
Control
|
0.14 proportion of positive responses
|
Adverse Events
Alcohol Messages
Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths
Serious adverse events
Adverse event data not reported
Other adverse events
Adverse event data not reported
Additional Information
Marissa Hall, PhD
University of North Carolina at Chapel Hill
Phone: 919-445-1310
Email: [email protected]
Results disclosure agreements
- Principal investigator is a sponsor employee
- Publication restrictions are in place