Universally Delivered Interventions for Young People

NCT ID: NCT06442007

Last Updated: 2024-12-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

564 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-05-01

Study Completion Date

2025-12-30

Brief Summary

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Mental health problems are amongst the major contributors to disease burden globally.

According to a recent study, 34% of young people worldwide (aged 10-19) suffer from depression and more than half of this population belongs to Southeast Asia such as Pakistan, India, and China.

Existing evidence shows that the access to mental health services in LMICs is limited and even fewer child psychiatric services are available.

One approach to overcome barriers such as limited availability of trained mental health professionals and risk of stigma may involve the use of simple, brief, scalable interventions based on basic psychological principles rather than treatment of psychopathology.

This study adapts and evaluates two brief interventions called behavioral activation single session intervention (BA-SSI) and 4-session Mindset intervention (MI) for teenage depression and anxiety in Pakistan, where access to mental health care is constrained by societal stigma and a shortage of clinicians.

Detailed Description

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A 3-arm multi-center cluster exploratory Randomized Controlled Trial to determine the feasibility, acceptability and preliminary effectiveness of a universally delivered, culturally adapted, potentially low cost, 4-session Mindset intervention (MI) and behavioral activation single session intervention (BA-SSI) for school going young persons (YP) (12-15 years) in Pakistan.

Proposed study is designed using the updated Medical Research Council (MRC) Framework for the development and evaluation of complex interventions.

Three public schools will be recruited from each of 10 cities across Pakistan: Karachi, Hyderabad, Nawabshah, Thatta, Lahore, Gujrat, Rawalpindi, Multan, Quetta, and Peshawar.

All the participants, regardless of their treatment arm, will be assessed at baseline, 1 month post-baseline and at 3-month.

Conditions

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Distress, Emotional

Keywords

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adolescents anxiety depression single session interventions growth mindset Pakistan

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Three arm study. Schools would be the unit of cluster.
Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Behavioral Activation - single session intervention (BA-SSI)

This is comprised of 5 five components:

1. Discussion on the rationale of the behavioral activation
2. Awareness raising about distress, including how behavior shapes feelings and thoughts;
3. a life values assessment
4. the creation of an activity action plan
5. an exercise in which youths write about benefits that might result from engaging in each activity, an obstacle that might keep them from doing the activities and a strategy for overcoming the identified obstacles.

Group Type EXPERIMENTAL

Behavioral Activation - single session intervention (BA-SSI)

Intervention Type BEHAVIORAL

Single session intervention

4-session Mindset intervention

This is comprised of a growth mindset module (2 sessions), a gratitude module (1 session) and a value affirmations module (1 session). Sessions are delivered weekly (over 4 weeks) and each session lasts for an hour. Reading and writing activities and group discussions are included in each session. Participants are supposed to complete homework exercises are assigned between sessions.

Group Type ACTIVE_COMPARATOR

4-session Mindset intervention

Intervention Type BEHAVIORAL

This is comprised of 4 sessions.

Waiting list control group

At end of the study, this group will be offered to choose one intervention from two active interventions mentioned above.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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Behavioral Activation - single session intervention (BA-SSI)

Single session intervention

Intervention Type BEHAVIORAL

4-session Mindset intervention

This is comprised of 4 sessions.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Youth is between the age 12-15 years (inclusive) at the time of study enrollment.
* Youth has one parent or legal guardian to give consent.
* Youth speaks Urdu well enough to complete the paper based intervention.


Schools in the study areas are eligible to participate if they meet all the following criteria:

1. the school authority agrees to participate;
2. the schools shall be non-specialist public schools;

Exclusion Criteria

* Intellectual disability, as this may undermine comprehension of intervention material.
* Adolescent with history of hospitalization or those who received inpatient treatment for a mental health problem within the past two months as the intervention being tested and this study is not designed for adolescent with acute medical and/or psychiatric treatment needs (if identified with any acute medical and/or psychiatric problem, they would be referred to appropriate health services through parents).



1. the school authority refuses to participate;
2. a specialist and/or independent or private school;
Minimum Eligible Age

12 Years

Maximum Eligible Age

15 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Fatima Jinnah Women University

OTHER

Sponsor Role collaborator

Pakistan Institute of Living and Learning

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Public school for boys 1

Rawalpindi, Punjab Province, Pakistan

Site Status

Countries

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Pakistan

Central Contacts

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Tayyeba Kiran, PhD

Role: CONTACT

Phone: 0923328262142

Email: [email protected]

Facility Contacts

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Tayyeba Kiran, PhD

Role: primary

Other Identifiers

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Mindset-PK

Identifier Type: -

Identifier Source: org_study_id