Acute Effects of HIIT vs. MICT on HRV

NCT ID: NCT06437145

Last Updated: 2024-05-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-02-15

Study Completion Date

2024-06-15

Brief Summary

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Heart rate variability (HRV) is impaired in patients after myocardial infarction. Most studies so far have proved chronic beneficial effects of different types of exercise on HRV parameters. Data on acute effects of different types of exercise training (e.g. high intensity interval training \[HIIT\] and moderate intensity continuous training \[MICT\]) is scarce.

Patients in the study will perform both HIIT and MICT in a random order and in-between break of at least 48 hours. A 5-minute high resolution ECG recording will be performed before and immediately after both HIIT and MICT.

Detailed Description

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Conditions

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Myocardial Infarction

Keywords

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exercise training high intensity interval training moderate intensity continuous training heart rate variability myocardial infarction

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Each patient will have a bout of HIIT during one session and a bout of MICT during another session performed in a random order.
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors
HRV parameters analysis will be blinded regarding the exercise training modality.

Study Groups

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High intensity interval training (HIIT)

The high-intensity interval training session consists of 5-min warm-up and 5-min cool-down periods. The main part has 7 cycles. Each cycle consists of 1.5 min of 80-90% of HRpeak and 3 min of 65-70% of HRpeak.

Group Type ACTIVE_COMPARATOR

Type of Exercise

Intervention Type OTHER

The high-intensity interval training session consists of 5-min warm-up and 5-min cool-down periods. The main part has 7 cycles. Each cycle consists of 1.5 min of 80-90% of HRpeak and 3 min of 65-70% of HRpeak. The moderate-intensity continuous training session consists of 5 min warm-up and 3-min cool down period. The main part consists of 32 min of 75% of HRpeak.

Moderate intensity continuous training (MICT)

The moderate-intensity continuous training session consists of 5 min warm-up and 3-min cool down period. The main part consists of 32 min of 75% of HRpeak.

Group Type ACTIVE_COMPARATOR

Type of Exercise

Intervention Type OTHER

The high-intensity interval training session consists of 5-min warm-up and 5-min cool-down periods. The main part has 7 cycles. Each cycle consists of 1.5 min of 80-90% of HRpeak and 3 min of 65-70% of HRpeak. The moderate-intensity continuous training session consists of 5 min warm-up and 3-min cool down period. The main part consists of 32 min of 75% of HRpeak.

Interventions

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Type of Exercise

The high-intensity interval training session consists of 5-min warm-up and 5-min cool-down periods. The main part has 7 cycles. Each cycle consists of 1.5 min of 80-90% of HRpeak and 3 min of 65-70% of HRpeak. The moderate-intensity continuous training session consists of 5 min warm-up and 3-min cool down period. The main part consists of 32 min of 75% of HRpeak.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* myocardial infarction in last 120 days
* sinus rhythm

Exclusion Criteria

* contraindications for exercise training
* uncontrolled dysrhythmias
* Heart Failure NYHA IV stage
* cognitive impairment
* pregnancy
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Medical Centre Ljubljana

OTHER

Sponsor Role lead

Responsible Party

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Borut Jug

Prof.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Marko Novaković, MD, PhD

Role: STUDY_CHAIR

University Medical Centre Ljubljana

Locations

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University Medical Centre Ljubljana

Ljubljana, , Slovenia

Site Status RECRUITING

Countries

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Slovenia

Central Contacts

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Marko Novaković, MD, PhD

Role: CONTACT

Phone: 0038615228032

Email: [email protected]

Facility Contacts

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Marko Novaković, MD, PhD

Role: primary

References

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Routledge FS, Campbell TS, McFetridge-Durdle JA, Bacon SL. Improvements in heart rate variability with exercise therapy. Can J Cardiol. 2010 Jun-Jul;26(6):303-12. doi: 10.1016/s0828-282x(10)70395-0.

Reference Type BACKGROUND
PMID: 20548976 (View on PubMed)

El-Malahi O, Mohajeri D, Mincu R, Bauerle A, Rothenaicher K, Knuschke R, Rammos C, Rassaf T, Lortz J. Beneficial impacts of physical activity on heart rate variability: A systematic review and meta-analysis. PLoS One. 2024 Apr 5;19(4):e0299793. doi: 10.1371/journal.pone.0299793. eCollection 2024.

Reference Type BACKGROUND
PMID: 38578755 (View on PubMed)

Grassler B, Thielmann B, Bockelmann I, Hokelmann A. Effects of different exercise interventions on heart rate variability and cardiovascular health factors in older adults: a systematic review. Eur Rev Aging Phys Act. 2021 Nov 17;18(1):24. doi: 10.1186/s11556-021-00278-6.

Reference Type BACKGROUND
PMID: 34789148 (View on PubMed)

Other Identifiers

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UKCLRehab2024/1

Identifier Type: -

Identifier Source: org_study_id