The Association Between Core Temperature and Health

NCT06432491 · Status: RECRUITING · Phase: NA · Type: INTERVENTIONAL · Enrollment: 36

Last updated 2026-01-21

No results posted yet for this study

Summary

The goal of this clinical trial is to learn if cold water drinking could promote body composition and further extend healthy lifespan in Chinese older adults. The main questions it aims to answer are:

1. Does cold water drinking lower the body fat percentage?
2. Will cold water drinking positively extend lifespan in a long-term Researchers will compare cold water intervention group to a control group (drinking 37℃ water instead) to see if cold water drinking works to promote health and slow down ageing process.

Participants will:

1. Drink 4℃ or 37℃ water 4 times (9a.m., 12p.m., 15p.m., 18p.m.) every day for 6 months.
2. Visit the institute and health checkup department for tests and checkup at baseline, the end of the 3rd month, and the end of 6th month.

Conditions

  • Body Temperature Changes
  • Body Composition
  • Aging

Interventions

BEHAVIORAL

Drinking cold water

Volunteers in the intervention group will be asked to drink up 500 ml 4℃ water within 10 minutes four times per day throughout the study.

Sponsors & Collaborators

  • Shenzhen University General Hospital

    collaborator OTHER
  • The Hong Kong Polytechnic University

    collaborator OTHER
  • Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences

    lead OTHER

Principal Investigators

  • John R Speakman, PhD · Shenzhen Institutes of Advanced Technology ,Chinese Academy of Sciences

Study Design

Allocation
RANDOMIZED
Purpose
PREVENTION
Masking
DOUBLE
Model
PARALLEL

Eligibility

Min Age
50 Years
Max Age
65 Years
Sex
ALL
Healthy Volunteers
Yes

Timeline & Regulatory

Start
2025-01-01
Primary Completion
2026-06-30
Completion
2026-12-31

Countries

  • China

Study Locations

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Read the full study record

This page highlights key information. For complete eligibility criteria, study locations, investigator contacts, and the full protocol, visit the original record on ClinicalTrials.gov.

View NCT06432491 on ClinicalTrials.gov