Clinical Validation of BACTEC™ Plus Aerobic/F Culture Vials Compared With Equivalent Product

NCT ID: NCT06426121

Last Updated: 2025-11-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

394 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-06-26

Study Completion Date

2025-10-23

Brief Summary

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This study is a multi-center, randomized clinical validation. Subjects should be fully informed of this protocol and related risks, and can only be enrolled into this study after signing the informed consent form. Blood collection of the subjects at the same puncture point at a single site will be injected into the test vial and the control vial respectively, and the vials will be transferred to the BACTEC system for culture and the results will be observed. After the BACTEC system incubation completion, the vials will be subcultured. Strains grown on plates will be identified using appropriate methods and, if possible, at the species level.

Detailed Description

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Conditions

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Sepsis

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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BD BACTEC™ Plus Aerobic/F Culture Vials(test)

Additional blood sample collected compared to clinical routine care

test Aerobic/F Culture Vials

Intervention Type DIAGNOSTIC_TEST

an additional blood sample will be collected compared to clinical routine of blood culture, inoculated into the test culture vial, and compared with the blood culture results of the control vial collected from the same site and the same puncture point

BD BACTEC™ Plus Aerobic/F Culture Vials(control)

clinical routine care

control Aerobic/F Culture Vials

Intervention Type DIAGNOSTIC_TEST

according to the clinical routine of blood culture, this blood sample should be collected and inoculated into the control vial, and its culture result will be collected

Interventions

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test Aerobic/F Culture Vials

an additional blood sample will be collected compared to clinical routine of blood culture, inoculated into the test culture vial, and compared with the blood culture results of the control vial collected from the same site and the same puncture point

Intervention Type DIAGNOSTIC_TEST

control Aerobic/F Culture Vials

according to the clinical routine of blood culture, this blood sample should be collected and inoculated into the control vial, and its culture result will be collected

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Subject is willing to provide written informed consent to sponsor.
* Blood specimens
* Patients with suspected blood infection that have one or more of the following characteristics :

a) Body temperature \> 38°C or body temperature \<36°C; b) chills; c) increased peripheral blood leukocyte count (count \> 10.0×109/L, especially if there is a "left shift") or decrease (count \< 3.0×109/L); d) Respiratory rate \> 20 beats/min or arterial partial pressure of carbon dioxide (PaCO2) \<32mmHg; e) Heart rate\> 90 beats/min; f) mucocutaneous hemorrhage; g) coma; h) Multi-organ dysfunction; i) decreased blood pressure; j) Elevated inflammatory response parameters such as C-reactive protein or hypersensitive C-reactive protein, procalcitonin (PCT), 1,3-β-D-glucan (G test), etc.

Exclusion Criteria

* Subjects have been enrolled in this study and samples have been collected
* Patients with severe and very severe anemia (last hemoglobin \<60g/L within seven days)
* Females with known pregnancy
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Becton, Dickinson and Company

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Peking University People's Hospital

Beijing, Beijing Municipality, China

Site Status

Countries

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China

Other Identifiers

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IDS-23CNBAC01

Identifier Type: -

Identifier Source: org_study_id

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