Efficacy and Safety Study of BHV-7000 Monotherapy in Major Depression
NCT ID: NCT06419608
Last Updated: 2026-01-07
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
PHASE2
336 participants
INTERVENTIONAL
2024-05-28
2025-11-07
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
QUADRUPLE
Study Groups
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BHV-7000
BHV-7000
BHV-7000 75 mg taken once daily for 6 weeks
Placebo
Placebo
Matching placebo taken once daily for 6 weeks
Interventions
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BHV-7000
BHV-7000 75 mg taken once daily for 6 weeks
Placebo
Matching placebo taken once daily for 6 weeks
Eligibility Criteria
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Inclusion Criteria
2. Subjects experiencing a current episode of depression for at least 2 months.
3. Subjects must be willing to discontinue all psychotropic medications (other medications to treat depression) before entering the study.
4. Male and Female participants 18 to 75 years of age at the time of consent.
5. Body Mass Index (BMI) must be ≥ 18 kg/m2 and ≤ 35 kg/m2.
Exclusion Criteria
2. Subjects with a history of bipolar disorder, schizophrenia, or other neuropsychiatric conditions that may interfere with the conduct of the study.
3. Subjects with a history of medical conditions that may interfere with the conduct of the study.
4. Females who are pregnant, breastfeeding or planning to become pregnant.
18 Years
75 Years
ALL
No
Sponsors
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Biohaven Therapeutics Ltd.
INDUSTRY
Responsible Party
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Locations
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IMA Clinical Research
Phoenix, Arizona, United States
Pillar Clinical Research, LLC
Little Rock, Arkansas, United States
WIRG
Little Rock, Arkansas, United States
WRN
Rogers, Arkansas, United States
Advanced Research Center, Inc.
Anaheim, California, United States
CIT LA
Bellflower, California, United States
IPMG
Chino, California, United States
WR-PRI Encino
Encino, California, United States
Collaborative Neuroscience Research, LLC (CenExel - CNS)
Garden Grove, California, United States
CalNeuro Research Group
Los Angeles, California, United States
Excell Research, Inc.
Oceanside, California, United States
NRC Research Institute
Orange, California, United States
Anderson Clinical Research
Redlands, California, United States
CIT IE
Riverside, California, United States
Lumos Clinical Research Center
San Jose, California, United States
Stanford
Stanford, California, United States
Cenexel CNS
Torrance, California, United States
Pacific Clinical Research Management Group
Upland, California, United States
Sunwise Clinical Research
Walnut Creek, California, United States
MCB Clinical Research Centers
Colorado Springs, Colorado, United States
UConn Health
Farmington, Connecticut, United States
Optum Behavioral Care of Connecticut, PC dba Comprehensive Psychiatric Care of Connecticut
Norwich, Connecticut, United States
Clinical Neuroscience Solutions, Inc
Jacksonville, Florida, United States
Floridian Neuroscience Institute
Miami Lakes, Florida, United States
Clinical Neuroscience Solutions, Inc.
Orlando, Florida, United States
K2 Medical Research
Tampa, Florida, United States
Neuroscience Research Institute
West Palm Beach, Florida, United States
CenExel iResearch, LLC
Decatur, Georgia, United States
CenExel iResearch, LLC
Savannah, Georgia, United States
Uptown Research Institute
Chicago, Illinois, United States
Revive Research Institute, Inc.
Elgin, Illinois, United States
Collective Medical Research
Overland Park, Kansas, United States
Delricht Research
New Orleans, Louisiana, United States
Headlands Pharmasite
Baltimore, Maryland, United States
CBH Health
Gaithersburg, Maryland, United States
Copley Clinical
Boston, Massachusetts, United States
Boston Clinical Trials
Boston, Massachusetts, United States
Adams Clinical
Watertown, Massachusetts, United States
Precise Clinical Research
Flowood, Mississippi, United States
Arch Clinical Trials
St Louis, Missouri, United States
IMA Clinical Research
Las Vegas, Nevada, United States
Bio Behavioral Health
Toms River, New Jersey, United States
SPRI Clinical Trials, LLC
Brooklyn, New York, United States
Neurobehavioral Research, Inc
Cedarhurst, New York, United States
Bioscience Research LLC
Mount Kisco, New York, United States
Berman Clinical
New York, New York, United States
Icahn School of Medicine at Mount Sinai
New York, New York, United States
The Medical Research Network, LLC
New York, New York, United States
RBA
Staten Island, New York, United States
Lehigh Center for Clinical Research
Allentown, Pennsylvania, United States
Suburban Research Associates
Media, Pennsylvania, United States
Scranton Medical Institute
Moosic, Pennsylvania, United States
Coastal Carolina Research Center
North Charleston, South Carolina, United States
Donald J. Garcia, MD, PA dba Austin Clinical Trial Partners
Austin, Texas, United States
FutureSearch Trials of Dallas
Dallas, Texas, United States
Relaro Medical Trials, LLC
Dallas, Texas, United States
InSite Clinical Research, LLC
DeSoto, Texas, United States
Red Oak Psychiatry Associates, PA
Houston, Texas, United States
Aim Trials
Plano, Texas, United States
Grayline Research Center
Wichita Falls, Texas, United States
Alpine Reseach Organization
Clinton, Utah, United States
Northwest Clinical Research Center
Bellevue, Washington, United States
Countries
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Other Identifiers
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BHV7000-305
Identifier Type: -
Identifier Source: org_study_id
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