Recording of Physiological Data Via an Optical Sensor At the Fingertip Alongside with Double Auscultatory and Pulse Oximetry to Evaluate the Effectiveness of an Optical Blood Pressure Monitoring (OBPM)

NCT ID: NCT06368206

Last Updated: 2024-12-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

85 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-06-25

Study Completion Date

2025-12-31

Brief Summary

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The present study, OBPM\_Calfree2024, with N = 85 participants minimum over 1 visit (lasting around 1h), has been designed to collect raw optical data with Aktiia.product-G2C Clinical investigational system together with several reference systems within a cohort of subjects characterized by a wide variety of phenotypes.

Detailed Description

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Conditions

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Hypertension

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

1 study cohort that will test investigational device (Aktiia G2C) and Blood Pressure and Pulse Rate references.
Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Aktiia G2C and references/ comparators for Blood Pressure and Pulse Rate monitoring

All study participants will test the investigational device (Aktiia G2C) and other marketed devices for blood pressure and pulse rate measurements (Aktiia Bracelet G2, Double auscultation, oscillometric monitors, finger pulse oximeter).

Group Type OTHER

Investigational device Aktiia G2C

Intervention Type DEVICE

Study subjects are asked to stay seated and relaxed while successive measurements are taken with Aktiia G2C.

Marketed device used as reference for blood pressure monitoring: double auscultation cuff

Intervention Type DEVICE

Study subjects are asked to stay seated and relaxed while successive measurements are taken with cuff for double auscultation.

Marketed device used as comparative device for blood pressure and pulse rate monitoring: Aktiia Bracelet G2

Intervention Type DEVICE

Study subjects are asked to stay seated and relaxed while successive measurements are taken with Aktiia Bracelet G2.

Marketed device used as comparative device for blood pressure and pulse rate monitoring: oscillometric upper-arm cuff

Intervention Type DEVICE

Study subjects are asked to stay seated and relaxed while taking successive measurements with an oscillometric upper-arm cuff.

Marketed device used as comparative device for blood pressure and pulse rate monitoring: oscillometric wrist cuff

Intervention Type DEVICE

Study subjects are asked to stay seated and relaxed while taking successive measurements with an oscillometric wrist cuff.

Marketed device used as reference for pulse rate monitoring: pulse finger oximeter

Intervention Type DEVICE

Study subjects are asked to stay seated and relaxed while successive measurements are taken with pulse finger oximeter.

Interventions

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Investigational device Aktiia G2C

Study subjects are asked to stay seated and relaxed while successive measurements are taken with Aktiia G2C.

Intervention Type DEVICE

Marketed device used as reference for blood pressure monitoring: double auscultation cuff

Study subjects are asked to stay seated and relaxed while successive measurements are taken with cuff for double auscultation.

Intervention Type DEVICE

Marketed device used as comparative device for blood pressure and pulse rate monitoring: Aktiia Bracelet G2

Study subjects are asked to stay seated and relaxed while successive measurements are taken with Aktiia Bracelet G2.

Intervention Type DEVICE

Marketed device used as comparative device for blood pressure and pulse rate monitoring: oscillometric upper-arm cuff

Study subjects are asked to stay seated and relaxed while taking successive measurements with an oscillometric upper-arm cuff.

Intervention Type DEVICE

Marketed device used as comparative device for blood pressure and pulse rate monitoring: oscillometric wrist cuff

Study subjects are asked to stay seated and relaxed while taking successive measurements with an oscillometric wrist cuff.

Intervention Type DEVICE

Marketed device used as reference for pulse rate monitoring: pulse finger oximeter

Study subjects are asked to stay seated and relaxed while successive measurements are taken with pulse finger oximeter.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Subjects aged 21 to 85yo
* Subjects fluent in written and spoken French
* Subjects agreeing to attend the study visit and follow study procedures
* Subjects that have signed the informed consent form.

Exclusion Criteria

* Amputated index fingers
* Damaged/injured skin at index fingers
* Damaged/injured skin at wrists
* Subjects suffering from sustained cardiac arrhythmias that can lead to weak or unstable pressure pulses including tachycardia (heart rate at rest \> 120bpm) and atrial fibrillation
* Subjects suffering from pathologies that systematically reduce peripheral perfusion including Raynaud's disease, diabetes, renal dysfunctions (eGFR \< 30mL/min/1.73 m2), hyper-/hypothyroidism, pheochromocytoma or arteriovenous fistula
* Pregnant women
* Polyneuropathy
Minimum Eligible Age

21 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Aktiia SA

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHUV

Lausanne, , Switzerland

Site Status RECRUITING

Countries

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Switzerland

Central Contacts

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Grégoire Wuerzner, Medical Doctor Prof.

Role: CONTACT

Phone: +41213140223

Email: [email protected]

Facility Contacts

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Grégoire Wuerzner, MD Prof

Role: primary

Other Identifiers

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OBPM_Calfree2024

Identifier Type: -

Identifier Source: org_study_id