Opioid Dispenser for Microdiscectomy/Laminectomy

NCT ID: NCT06358040

Last Updated: 2025-12-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2026-10-31

Study Completion Date

2026-12-31

Brief Summary

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The opioid crisis continues to plague the United States. While great strides have been made nationwide to decrease overprescribing, improvements are still needed to appropriately educate patients on the safe and responsible use, storage and disposal of opioids. Pain after surgery is often treated with opioid medications. Opioid medications can have side effects. Some side effects are relatively minor (constipation, nausea, vomiting), while others are more severe (sedation, abnormal breathing, etc.) and can lead to serious illness or death. Opioid pain medications when used the wrong way may also be addictive. Due to theses side effects, sometimes patients feel uncomfortable about taking these medications, and doctors prescribe them very cautiously. However, when used properly and safely, opioid pain medications are excellent pain relievers.

Addinex, a technology company, has developed a device to help patients take opioids more safely. In this study the investigators aim to enroll a total of 30 patients who undergo spine surgery. Half will be randomly assigned to receive a standard pill bottle with opioids at discharge and will download a mobile app so that they can record their daily pain scores and the number of opioids they take for two weeks after surgery. The other half will receive the new opioid dispenser filled with opioids and a mobile app that generates a passcode that opens that device only at designated times. For this group of patients, every time the patient wants to take an opioid, they need to go to the app, enter their pain score before the app generates a passcode. The investigators will be tracking all study patients' opioid use and pain scores for the two weeks after surgery, will count how many pills they have left over 14 days after their surgery during a live telehealth session, and ask patients how they liked using the device. Results from this study will help understand if the Addinex device could potentially be useful to patients in the future after surgeries as opposed to typical pill bottles.

Detailed Description

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Conditions

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Opioid Use Pain, Postoperative Medical Device Laminectomy Diskectomy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Standard Opioid Pill Bottle with App

Group Type ACTIVE_COMPARATOR

App

Intervention Type OTHER

Addinex App

Standard Opioid Pill Bottle

Intervention Type OTHER

Standard Opioid Pill Bottle

Opioid-Dispensing Device with App

Group Type EXPERIMENTAL

Opioid-Dispensing Device

Intervention Type DEVICE

Addinex Opioid-Dispensing Device

App

Intervention Type OTHER

Addinex App

Interventions

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Opioid-Dispensing Device

Addinex Opioid-Dispensing Device

Intervention Type DEVICE

App

Addinex App

Intervention Type OTHER

Standard Opioid Pill Bottle

Standard Opioid Pill Bottle

Intervention Type OTHER

Other Intervention Names

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Addinex Addinex

Eligibility Criteria

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Inclusion Criteria

* opioid-naive patients or intermittent opioid users within 3 months of scheduled surgery
* At least 18 years old
* presenting for primary elective one-level lumbar laminectomy and/or discectomy via posterior approach with participating surgeon
* planned discharge on day of surgery/23 hour admission
* planned discharge to home

Exclusion Criteria

* patients with opioid-tolerance
* patients without a smart-phone or without the ability to perform Telehealth visits
* patients unable to utilize the medication dispensing device
* patients presenting for other surgeries/surgeries with combined anterior/lateral approaches
* patient refusal
* allergy or intolerance to opioids
* planned admission after surgery
* planned discharge disposition to nursing facility or skilled rehabilitation
* planned use of or preference for opioid other than oxycodone
* patients who are pregnant
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Hospital for Special Surgery, New York

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Vladimir Kramskiy, MD

Role: PRINCIPAL_INVESTIGATOR

Hospital for Special Surgery, New York

Locations

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Hospital for Special Surgery

New York, New York, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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William Chan, MEng

Role: CONTACT

917-260-4788

Alexandra Sideris, PhD

Role: CONTACT

212-774-2602

Facility Contacts

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William Chan, MEng

Role: primary

917-260-4788

Alexandra Sideris, PhD

Role: backup

212-774-2602

Other Identifiers

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2023-0328

Identifier Type: -

Identifier Source: org_study_id

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