Effect of Jing Si Herbal Tea Liquid Packets on Chronic Pharyngolaryngitis

NCT ID: NCT06331351

Last Updated: 2025-09-11

Basic Information

• Recruitment Status: RECRUITING
• Clinical Phase: NA
• Total Enrollment: 120 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-02-22
• Study Completion Date: 2025-12-31

Brief Summary

Chronic pharyngolaryngitis is common and often make people suffer in many aspects. The etiology is numerous, for example, airway hypersensitivity, gastroesophageal acid regurgitation, sicca syndrome, anxiety, etc.

The investigators aimed to investigate the effect of Jing Si herbal tea liquid packets on chronic pharyngolaryngitis by a design of randomized, double-blind clinical trial in this study. The subjects who were bed-ridden, without self-care ability, receiving hemodialysis, no idea about the details of this study, poor compliance for this study, alcohol and/or drugs additives, pregnancy and breast-feeding women were excluded from this study.

A questionnaire for health and habits was performed at the start of the study, and a questionnaire for Reflux Symptom Index (RSI) was performed at the start and the end of the study. Finally, Student's t-test was used to test the difference between the Jing Si herbal tea group and the control group. And, multivariate linear regression was used to test the violation of clinical factors on the treatment outcome of Jing Si herbal tea liquid packets on chronic pharyngolaryngitis.

Detailed Description

Chronic pharyngolaryngitis is common and often make people suffer in many aspects. The etiology is numerous, for example, airway hypersensitivity, gastroesophageal acid regurgitation, sicca syndrome, anxiety, etc.

The investigators aimed to investigate the effect of Jing Si herbal tea liquid packets on chronic pharyngolaryngitis by a design of randomized, double-blind clinical trial in this study. One hundred and twenty adults of both sex with a range of age between of 20-70 years old were included. All participants were divided randomly into two groups. Jing Si herbal tea group received 1 pack of Jing Si herbal tea liquid packet twice a day for 1 month (30 days), and the control group received 1 pack of control liquid packet twice a day for 1 month (30 days). The subjects who were bed-ridden, without self-care ability, receiving hemodialysis, no idea about the details of this study, poor compliance for this study, alcohol and/or drugs additives, pregnancy and breast-feeding women were excluded from this study.

A questionnaire for health and habits was performed at the start of the study, and a questionnaire for Reflux Symptom Index (RSI) was performed at the start and the end of the study. Finally, Student's t-test was used to test the difference between the Jing Si herbal tea group and the control group. And, multivariate linear regression was used to test the violation of clinical factors on the treatment outcome of Jing Si herbal tea liquid packets on chronic pharyngolaryngitis.

Conditions

Chronic Pharyngitis

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: OTHER
• Blinding Strategy: DOUBLE

Study Groups

control group

placebo: 2 times a day, 1 sachet each time.

Group Type: PLACEBO_COMPARATOR

control group

Intervention Type: OTHER

2 times a day, 1 sachet each time.

Jing Si herbal tea liquid packets group

Jing Si herbal tea liquid packets: 2 times a day, 1 sachet each time.

Group Type: EXPERIMENTAL

Jing Si herbal tea liquid packets

Intervention Type: OTHER

2 times a day, 1 sachet each time.

Interventions

control group

2 times a day, 1 sachet each time.

Intervention Type: OTHER

Jing Si herbal tea liquid packets

2 times a day, 1 sachet each time.

Intervention Type: OTHER

Other Intervention Names

Placebo

Eligibility Criteria

Inclusion Criteria

1. Adult men and women aged 20 to 70 years old.

2. Patients with chronic pharyngitis

Exclusion Criteria

1. Patients who are bedridden or unable to take care of themselves.

2. Dialysis patients.

3. Patients who cannot understand the details of this study or cannot cooperate with the examination.

4. History of alcohol or drug abuse.

5. Pregnant and lactating women

• Minimum Eligible Age: 20 Years
• Maximum Eligible Age: 70 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Dalin Tzu Chi General Hospital

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Juen-Haur Hwang, MD, PhD

Role: STUDY_CHAIR

Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation

Locations

Dalin Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation

Chiayi City, , Taiwan

Site Status: RECRUITING

Countries

Taiwan

Central Contacts

Juen-Haur Hwang, MD, PhD

Role: CONTACT

g120796@tzuchi.com.tw

+886-5-2648000 ext. 5239

Facility Contacts

Juen-Haur Hwang, MD, PhD

Role: primary

g120796@tzuchi.com.tw

+886-5-2648000 ext. 5239

Other Identifiers

A11203001-1

Identifier Type: -

Identifier Source: org_study_id