Trial Outcomes & Findings for A Study Evaluating the Safety of the Nasal Pump (NCT NCT06329687)

NCT ID: NCT06329687

Last Updated: 2025-05-02

Results Overview

Number of Participants with Adverse Events with the nasal pump with additional silicone lubricant

Recruitment status

TERMINATED

Study phase

PHASE4

Target enrollment

5 participants

Primary outcome timeframe

7 days

Results posted on

2025-05-02

Participant Flow

Participant milestones

Participant milestones
Measure
Nasal Pump
Tyrvaya nasal pump with additional silicone lubricant Tyrvaya Nasal Pump: Tyrvaya Nasal Pump with Silicone Lubricant
Overall Study
STARTED
5
Overall Study
COMPLETED
5
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

A Study Evaluating the Safety of the Nasal Pump

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Nasal Pump
n=5 Participants
Tyrvaya nasal pump with additional silicone lubricant Tyrvaya Nasal Pump: Tyrvaya Nasal Pump with Silicone Lubricant
Age, Continuous
68.8 years
STANDARD_DEVIATION 15.0 • n=5 Participants
Sex: Female, Male
Female
4 Participants
n=5 Participants
Sex: Female, Male
Male
1 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
2 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
3 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=5 Participants
Race (NIH/OMB)
Asian
1 Participants
n=5 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=5 Participants
Race (NIH/OMB)
Black or African American
0 Participants
n=5 Participants
Race (NIH/OMB)
White
4 Participants
n=5 Participants
Race (NIH/OMB)
More than one race
0 Participants
n=5 Participants
Race (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants

PRIMARY outcome

Timeframe: 7 days

Number of Participants with Adverse Events with the nasal pump with additional silicone lubricant

Outcome measures

Outcome measures
Measure
Nasal Pump
n=5 Participants
Tyrvaya nasal pump with additional silicone lubricant Tyrvaya Nasal Pump: Tyrvaya Nasal Pump with Silicone Lubricant
Number of Participants With Adverse Events
1 Participants

Adverse Events

Nasal Pump

Serious events: 0 serious events
Other events: 1 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Other adverse events
Measure
Nasal Pump
n=5 participants at risk
Tyrvaya nasal pump with additional silicone lubricant Tyrvaya Nasal Pump: Tyrvaya Nasal Pump with Silicone Lubricant
General disorders
Instillation Site Irritation
20.0%
1/5 • AE collection will start following the first administration of Tyrvaya® with additional silicone lubricant until the last follow up visit of the study at 7 days.
The safety population will include all enrolled subjects who received at least one Tyrvaya ®administered with the additional silicone lubricant.

Additional Information

Marian Macsai, MD

Oyster Point Pharma Inc

Phone: 3122592477

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place