Social Network Overdose Prevention and Education Intervention

NCT ID: NCT06327061

Last Updated: 2025-03-10

Basic Information

• Recruitment Status: RECRUITING
• Clinical Phase: NA
• Total Enrollment: 600 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-06-01
• Study Completion Date: 2028-04-29

Brief Summary

The purpose of this study is to test a social intervention focused on overdose prevention and care. In the investigators prior work, the investigators have shown that people who use opioids (PWUO) can be effective peer educators (PEs).

Detailed Description

The purpose of this study is to test a social intervention focused on overdose prevention and care. In the investigators prior work, the investigators have shown that people who use opioids (PWUO) can be effective peer educators (PEs). The investigators have utilized PEs for overdose prevention in interventions that have focused on training network members who use drugs to respond to an overdose. Yet, many overdoses are witnessed by people who do not use drugs. Additionally, many PWUO report using drugs at home and living with someone who does not use drugs, which highlights the importance of training non-using network members on overdose response. Based on pilot data, the investigators propose expanding an overdose peer education intervention to focus on non-using network members. The intervention seeks to prepare network members to respond to an overdose and normalize discussions about overdose prevention planning between index PWUO and non-using network members. The intervention condition consists of 3 individual sessions focused on overdose prevention and response. This condition is designed to train index study participants to be Peer Educators. In addition to the three sessions, the non-drug using network member will be offered one session. The control condition is only 1 session focused on overdose prevention and response. Both intervention and control participants will invite social network members to take part in data collection activities

Conditions

Drug Overdose

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: SINGLE

Study Groups

Experimental: Peer education and network support

During sessions 1 and 2, participants will be taught information and skills pertaining to overdose prevention and response. During the 3rd session, participants will trained to talk to their non drug using network members in overdose prevention and response.

Group Type: EXPERIMENTAL

Network overdose prevention

Intervention Type: BEHAVIORAL

Participants are taught overdose prevention methods with network members.

comparison: Standard of care of health education

In one session, participants will receive the standard of care for overdose prevention.

Group Type: ACTIVE_COMPARATOR

Standard of care health education

Intervention Type: BEHAVIORAL

Participants will receive the standard of care for overdose prevention.

Interventions

Network overdose prevention

Participants are taught overdose prevention methods with network members.

Intervention Type: BEHAVIORAL

Standard of care health education

Participants will receive the standard of care for overdose prevention.

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• self-reported illicit opioid use at least 2 times in the past two weeks;
• age 18 and older;
• living in the Baltimore metropolitan region;
• willing to engage in peer education; and
• having and willing to recruit at least one non-using network member.

Exclusion Criteria

Participants without the cognitive ability to provide informed consent and have the physical ability to participate in in-person intervention sessions.

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

National Institute on Drug Abuse (NIDA)

NIH

Sponsor Role: collaborator

Johns Hopkins Bloomberg School of Public Health

OTHER

Sponsor Role: lead

Responsible Party

Responsibility Role: SPONSOR

Principal Investigators

Carl Latkin, PhD

Role: PRINCIPAL_INVESTIGATOR

Johns Hopkins University

Locations

Johns Hopkins Bloomberg School of Public Health

Baltimore, Maryland, United States

Site Status: RECRUITING

Countries

United States

Central Contacts

Carl Latkin, PhD

Role: CONTACT

carl.latkin@jhu.edu

(410)955-3972

Facility Contacts

Carl Latkin, PhD

Role: primary

clatkin@jhsph.edu

410-955-3972

Other Identifiers

IRB00026607

Identifier Type: OTHER

Identifier Source: secondary_id

R01DA058659

Identifier Type: NIH

Identifier Source: org_study_id

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