Evaluation of Next-Day Residual Effects of Tasimelteon Compared With Placebo and Active Control in Healthy Subjects

NCT ID: NCT06323655

Last Updated: 2024-03-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE1

Total Enrollment

48 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-07-19

Study Completion Date

2018-08-28

Brief Summary

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The aim of this study is to investigate next-day residual effects of tasimelteon compared with placebo and active control in healthy subjects.

Detailed Description

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Conditions

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Healthy Volunteers

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

QUADRUPLE

Participants Caregivers Investigators Outcome Assessors

Study Groups

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Tasimelteon

single dose

Group Type EXPERIMENTAL

Tasimelteon

Intervention Type DRUG

oral capsule

Active Control Placebo

Intervention Type DRUG

oral capsule

Placebo

single dose

Group Type PLACEBO_COMPARATOR

Active Control Placebo

Intervention Type DRUG

oral capsule

Tasimelteon Placebo

Intervention Type DRUG

oral capsule

Active Control

single dose

Group Type ACTIVE_COMPARATOR

Tasimelteon Placebo

Intervention Type DRUG

oral capsule

Active Control

Intervention Type DRUG

oral capsule

Interventions

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Tasimelteon

oral capsule

Intervention Type DRUG

Active Control Placebo

oral capsule

Intervention Type DRUG

Tasimelteon Placebo

oral capsule

Intervention Type DRUG

Active Control

oral capsule

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Ability to provide written consent;
* Healthy subjects with no medical, psychiatric, or current sleep disorders;
* Men and women ages 21 - 55, inclusive;
* Possession of a valid driver's license ≥ 3 years with reported annual mileage ≥ 3,000 km.

Exclusion Criteria

* Pregnancy or recent pregnancy;
* Subjects who are unable to read or speak English or French.
Minimum Eligible Age

21 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Vanda Pharmaceuticals

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Vanda Investigational Site

Laval, Quebec, Canada

Site Status

Countries

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Canada

Other Identifiers

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VP-VEC-162-1201

Identifier Type: -

Identifier Source: org_study_id

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