Trial Outcomes & Findings for Feasibility of Measuring Vertical Perception in Acute Stroke (NCT NCT06301815)

NCT ID: NCT06301815

Last Updated: 2025-06-08

Results Overview

The bucket test involves the patient being sat upright and looking into a translucent bucket. On the inside of the bucket on the bottom is a dark straight line. On the outside of the bottom of the bucket is a matching dark line, the bottom of the bucket is divided into degrees with the zero-degree line being equivalent to the line inside the bucket. For measurement the bucket will be randomly rotated right or left by the examiner to 45 degrees and then slowly rotated back to the zero-degree position. Patients will signal when they estimate the inside bottom line to be truly vertical by saying "stop" or by raising their non-paretic hand. Degrees will be read off on the outside scale by the examiner. The procedure will be repeated 6 times (3 to left and 3 to right) in a random order. A mean of the 6 tests will be calculated to be the tilt of SVV. The standard deviation (SD) of the mean of the 6 tests will be calculated to represent the uncertainty of SVV.

Recruitment status

COMPLETED

Target enrollment

53 participants

Primary outcome timeframe

Admission, 1 week, 2 weeks and 4 weeks, but not repeated once successfully completed.

Results posted on

2025-06-08

Participant Flow

Participants were recruited between 1/5/2024 and 31/10/2024 on the acute stroke unit at Hampshire Hospitals NHS Foundation Trust, UK.

No significant Events

Participant milestones

Participant milestones
Measure
Intervention Group
Participants who underwent the interventions as laid out in the protocol. As this was an observational study all participants underwent three assessments (bucket test, Catherine Bergego Scale and Scale for contraversive pushing) once on recruitment. There was only one group. These assessments were completed as soon as possible after admission to an acute stroke unit and were all completed by four weeks.
Overall Study
STARTED
53
Overall Study
COMPLETED
53
Overall Study
NOT COMPLETED
0

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Race and Ethnicity were not collected from any participant.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Intervention Group
n=53 Participants
Participants who underwent the interventions as laid out in the protocol
Age, Continuous
77 Years
n=53 Participants
Sex: Female, Male
Female
28 Participants
n=53 Participants
Sex: Female, Male
Male
25 Participants
n=53 Participants

PRIMARY outcome

Timeframe: Admission, 1 week, 2 weeks and 4 weeks, but not repeated once successfully completed.

The bucket test involves the patient being sat upright and looking into a translucent bucket. On the inside of the bucket on the bottom is a dark straight line. On the outside of the bottom of the bucket is a matching dark line, the bottom of the bucket is divided into degrees with the zero-degree line being equivalent to the line inside the bucket. For measurement the bucket will be randomly rotated right or left by the examiner to 45 degrees and then slowly rotated back to the zero-degree position. Patients will signal when they estimate the inside bottom line to be truly vertical by saying "stop" or by raising their non-paretic hand. Degrees will be read off on the outside scale by the examiner. The procedure will be repeated 6 times (3 to left and 3 to right) in a random order. A mean of the 6 tests will be calculated to be the tilt of SVV. The standard deviation (SD) of the mean of the 6 tests will be calculated to represent the uncertainty of SVV.

Outcome measures

Outcome measures
Measure
Intervention Group
n=53 Participants
Participants who underwent the interventions as laid out in the protocol
Bucket Test to Measure Subjective Visual Vertical (SVV).
3.2 Degrees
Standard Deviation 3.6

PRIMARY outcome

Timeframe: Admission, 1 week, 2 weeks and 4 weeks, but not repeated once successfully completed.

Neglect will be assessed using the Catherine Bergego Scale. This established outcome measure for neglect is free and observational, it reflects existing practice and therefore reduces the burden on research participants. The scale is a 10-point scale with each item scored between 0 (no neglect) and 3 (severe neglect). Such as grooming, walking, eating and dressing. Minimum score is 0 - no neglect and maximum score is 30 - severe neglect

Outcome measures

Outcome measures
Measure
Intervention Group
n=53 Participants
Participants who underwent the interventions as laid out in the protocol
Catherine Bergego Scale to Measure Neglect.
0 Units on a scale (0-30)
Interval 0.0 to 1.0

PRIMARY outcome

Timeframe: Admission, 1 week, 2 weeks and 4 weeks, but not repeated once succesfully completed.

Lateropulsion will be assessed using the Scale for Contraversive Pushing (SCP). This observational assessment can be conducted as part of routine therapy sessions. Scores are assessed in sitting and standing giving a maximum score of 6. The SCP has been found to be a reliable and valid measure. It involves observation of the posture of the patient in sitting and standing. Minimum score of 0 is no sign of lateropulsion and maximum score of 6 is severe lateropulsion.

Outcome measures

Outcome measures
Measure
Intervention Group
n=53 Participants
Participants who underwent the interventions as laid out in the protocol
Scale for Contraversive Pushing to Measure Lateropulsion
0 Units on a scale (0-6)
Interval 0.0 to 1.0

Adverse Events

Intervention Group

Serious events: 0 serious events
Other events: 0 other events
Deaths: 1 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Amelia Shaw

University of Winchester

Phone: 01962 717478

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place