TDCS Interventions for Subthreshold Depressive Symptoms in Young Individuals.
NCT ID: NCT06294184
Last Updated: 2024-12-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
RECRUITING
NA
150 participants
INTERVENTIONAL
2023-11-01
2025-12-31
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Keywords
Explore important study keywords that can help with search, categorization, and topic discovery.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
PREVENTION
TRIPLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
lDLPFC tdcs stimulation group
The current is 2mA, duration is 1200s, fade in 30s, fade out 30s, anode is on the F3, cathode is on the FP2.
tdcs lDLPFC
The current is 2mA, duration is 1200s, fade in 30s, fade out 30s, anode is on the F3, cathode is on the FP2.
rVLPFC tdcs stimulation group
The current is 2mA, duration is 1200s, fade in 30s, fade out 30s, anode is on the F6, cathode is on the FP1.
tdcs rVLPFC
The current is 2mA, duration is 1200s, fade in 30s, fade out 30s, anode is on the F6, cathode is on the FP1.
Sham group
The current only persist in the fisrt 30s, duration is 1200s, fade in 30s, fade out 30s, anode is on the F3/F6, cathode is on the FP2/1.
Sham
The current only persist in the fisrt 30s, duration is 1200s, fade in 30s, fade out 30s, anode is on the F3/F6, cathode is on the FP2/1.
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
tdcs lDLPFC
The current is 2mA, duration is 1200s, fade in 30s, fade out 30s, anode is on the F3, cathode is on the FP2.
tdcs rVLPFC
The current is 2mA, duration is 1200s, fade in 30s, fade out 30s, anode is on the F6, cathode is on the FP1.
Sham
The current only persist in the fisrt 30s, duration is 1200s, fade in 30s, fade out 30s, anode is on the F3/F6, cathode is on the FP2/1.
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* 2\) is right-handed on the Edinburgh Handedness Inventory;
* 3\) 2-4 of the 9 depressive symptoms defined by the American Diagnostic and Statistical Manual of Diseases, Fifth Edition (DSM-5), lasting more than 1 week; or more than 5 depressive symptoms lasting more than 1 week but less than 2 weeks (i.e., not meeting criteria for a major depressive episode) (by DSM-5 Clinical Semi-Definitive Interview (K-SADS-PL) (Gilbody et al., 2017, JAMA);
* 4\) Hamilton Depression Scale (HAMD-24) 24 pointsâ„ 8 points, \< 24 points;
* 5\) Gender is not limited;
* 6\) Subjects and their families voluntarily participate and sign the informed consent form.
Exclusion Criteria
* 2\) Have two or more DSM-V-defined manic symptoms for 4 days but do not meet the criteria for hypomania or meet the DSM-V defined criteria for hypomanic symptoms for only 2-3 days;
* 3\) Severe or unstable physical illness;
* 4\) have a moderate or higher risk of suicide (as assessed by the Columbia Suicide Severity Scale);
* 5\) Received transcranial direct current stimulation in the past three months (continuous intervention time: \>2 weeks);
* 6\) Contraindications to transcranial direct current stimulation, such as brain implants, personal or family history of epilepsy;
* 7\) Magnetic resonance scanning is contraindicated, such as in vivo metal implants.
12 Years
25 Years
ALL
Yes
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Guangzhou Psychiatric Hospital
OTHER_GOV
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Kangguang Lin
Professor
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Kangguang Lin, M.D;PH.D
Role: STUDY_DIRECTOR
The Affiliated Brain Hospital of Guangzhou Medical University
Robin Shao, Ph.D
Role: PRINCIPAL_INVESTIGATOR
The Affiliated Brain Hospital of Guangzhou Medical University
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
Guangzhou Brain hospital(Guangzhou Huiai Hospital)
Guangzhou, Guangdong, China
Countries
Review the countries where the study has at least one active or historical site.
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
Facility Contacts
Find local site contact details for specific facilities participating in the trial.
Kangguang Lin, M.D;Ph.D
Role: primary
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
Guangzhou PH tDCS in SD
Identifier Type: -
Identifier Source: org_study_id