Trial Outcomes & Findings for Health-Kit Enabled Mobile App for Tobacco Cessation (NCT NCT06292130)

NCT ID: NCT06292130

Last Updated: 2025-05-16

Results Overview

This reliable and valid 6-item assessment measures feelings of social disapproval of smoking, normative values associated with smoking, and negative beliefs about appearance when smoking (e.g., If I quit smoking I will be more in control of my life). It will be the primary outcome as it is appropriate for all smokers (ready to quit or not) and is highly correlated with interest in quitting (r=0.59). It is also correlated with recency of quit attempts. Participants respond on a 5-point Likert Scale from 0 (Not at all) to 4 (Very much). Raw scores range from a minimum of 0 to a maximum of 24, with higher scores indicating better outcomes. The reliability of the scale is 0.85.

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

51 participants

Primary outcome timeframe

Pretest (baseline) and Posttest (30 day follow-up)

Results posted on

2025-05-16

Participant Flow

Participant milestones

Participant milestones
Measure
App Users
All participants will be provided with access to the intervention app (refresh). refresh: A theoretically-grounded, highly individualized tobacco cessation Health-Kit enabled app. Unlike existing tobacco cessation apps, refresh: 1) implements a full range of best practices in tailored health behavior change communications; 2) individualizes messaging based on the patient's clinical context using Health app data obtained through Fast Healthcare Interoperability Resources (FHIR) standard Application Programming Interfaces (API) and behavior change constructs; and 3) provides data and key insights back to the electronic health record (EHR).
Overall Study
STARTED
51
Overall Study
COMPLETED
39
Overall Study
NOT COMPLETED
12

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

Health-Kit Enabled Mobile App for Tobacco Cessation

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
App Users
n=51 Participants
All participants will be provided with access to the intervention app (refresh). refresh: A theoretically-grounded, highly individualized tobacco cessation Health-Kit enabled app. Unlike existing tobacco cessation apps, refresh: 1) implements a full range of best practices in tailored health behavior change communications; 2) individualizes messaging based on the patient's clinical context using Health app data obtained through Fast Healthcare Interoperability Resources (FHIR) standard Application Programming Interfaces (API) and behavior change constructs; and 3) provides data and key insights back to the EHR.
Age, Categorical
<=18 years
0 Participants
n=5 Participants
Age, Categorical
Between 18 and 65 years
49 Participants
n=5 Participants
Age, Categorical
>=65 years
2 Participants
n=5 Participants
Age, Continuous
47.4 years
STANDARD_DEVIATION 11.3 • n=5 Participants
Sex: Female, Male
Female
38 Participants
n=5 Participants
Sex: Female, Male
Male
13 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Hispanic or Latino
8 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Not Hispanic or Latino
43 Participants
n=5 Participants
Ethnicity (NIH/OMB)
Unknown or Not Reported
0 Participants
n=5 Participants
Race (NIH/OMB)
American Indian or Alaska Native
1 Participants
n=5 Participants
Race (NIH/OMB)
Asian
1 Participants
n=5 Participants
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=5 Participants
Race (NIH/OMB)
Black or African American
24 Participants
n=5 Participants
Race (NIH/OMB)
White
18 Participants
n=5 Participants
Race (NIH/OMB)
More than one race
2 Participants
n=5 Participants
Race (NIH/OMB)
Unknown or Not Reported
5 Participants
n=5 Participants
Region of Enrollment
United States
51 participants
n=5 Participants

PRIMARY outcome

Timeframe: Pretest (baseline) and Posttest (30 day follow-up)

This reliable and valid 6-item assessment measures feelings of social disapproval of smoking, normative values associated with smoking, and negative beliefs about appearance when smoking (e.g., If I quit smoking I will be more in control of my life). It will be the primary outcome as it is appropriate for all smokers (ready to quit or not) and is highly correlated with interest in quitting (r=0.59). It is also correlated with recency of quit attempts. Participants respond on a 5-point Likert Scale from 0 (Not at all) to 4 (Very much). Raw scores range from a minimum of 0 to a maximum of 24, with higher scores indicating better outcomes. The reliability of the scale is 0.85.

Outcome measures

Outcome measures
Measure
App Users
n=39 Participants
All participants will be provided with access to the intervention app (refresh). refresh: A theoretically-grounded, highly individualized tobacco cessation Health-Kit enabled app. Unlike existing tobacco cessation apps, refresh: 1) implements a full range of best practices in tailored health behavior change communications; 2) individualizes messaging based on the patient's clinical context using Health app data obtained through Fast Healthcare Interoperability Resources (FHIR) standard Application Programming Interfaces (API) and behavior change constructs; and 3) provides data and key insights back to the EHR.
Psychosocial Expectancies (PROMIS Smoking Initiative) Patient Reported Outcome
Pretest (baseline)
12.7 score on a scale
Standard Deviation 6.8
Psychosocial Expectancies (PROMIS Smoking Initiative) Patient Reported Outcome
Posttest (30 day follow-up)
13.6 score on a scale
Standard Deviation 5.6

SECONDARY outcome

Timeframe: Pretest (baseline) and Posttest (30 day follow-up)

This 3-item scale assesses an individual's confidence level to refrain from using tobacco even in difficult situations and is a leading indicator of movement to cessation. Ratings of confidence will be made on a 5-point Likert scale (1=not at all; 5=extremely confident). Raw scores range from a minimum of 3 to a maximum of 15, with higher scores indicating better outcomes.

Outcome measures

Outcome measures
Measure
App Users
n=39 Participants
All participants will be provided with access to the intervention app (refresh). refresh: A theoretically-grounded, highly individualized tobacco cessation Health-Kit enabled app. Unlike existing tobacco cessation apps, refresh: 1) implements a full range of best practices in tailored health behavior change communications; 2) individualizes messaging based on the patient's clinical context using Health app data obtained through Fast Healthcare Interoperability Resources (FHIR) standard Application Programming Interfaces (API) and behavior change constructs; and 3) provides data and key insights back to the EHR.
Confidence
Pretest (baseline)
6.3 score on a scale
Standard Deviation 2.5
Confidence
Posttest (30 day follow-up)
7.6 score on a scale
Standard Deviation 2.7

Adverse Events

App Users

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Sara Johnson, PhD

Pro-Change Behavior Systems, Inc.

Phone: 401.360.2980

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place