A Study to Evaluate the Efficacy and Safety of AD-224

NCT ID: NCT06291207

Last Updated: 2025-02-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

PHASE3

Total Enrollment

252 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-04-15

Study Completion Date

2025-07-31

Brief Summary

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The purpose of this study is to evaluate the efficacy and safety of AD-224

Detailed Description

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Condition or disease : Essential Hypertension

Conditions

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Hypertension,Essential

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Investigators

Study Groups

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AD-224A

AD-224A+Placebo of AD-224B+Placebo of AD-224C

Group Type EXPERIMENTAL

AD-224A

Intervention Type DRUG

PO, Once daily, 8weeks

Placebo of AD-224B

Intervention Type DRUG

PO, Once daily, 8weeks

Placebo of AD-224C

Intervention Type DRUG

PO, Once daily, 8weeks

AD-224B

Placebo of AD-224A+AD-224B+Placebo of AD-224C

Group Type EXPERIMENTAL

AD-224B

Intervention Type DRUG

PO, Once daily, 8weeks

Placebo of AD-224A

Intervention Type DRUG

PO, Once daily, 8weeks

Placebo of AD-224C

Intervention Type DRUG

PO, Once daily, 8weeks

AD-224C

Placebo of AD-224A+Placebo of AD-224B+AD-224C

Group Type ACTIVE_COMPARATOR

AD-224C

Intervention Type DRUG

PO, Once daily, 8weeks

Placebo of AD-224A

Intervention Type DRUG

PO, Once daily, 8weeks

Placebo of AD-224B

Intervention Type DRUG

PO, Once daily, 8weeks

Interventions

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AD-224A

PO, Once daily, 8weeks

Intervention Type DRUG

AD-224B

PO, Once daily, 8weeks

Intervention Type DRUG

AD-224C

PO, Once daily, 8weeks

Intervention Type DRUG

Placebo of AD-224A

PO, Once daily, 8weeks

Intervention Type DRUG

Placebo of AD-224B

PO, Once daily, 8weeks

Intervention Type DRUG

Placebo of AD-224C

PO, Once daily, 8weeks

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* Signed informed consent
* Patients with Essential Hypertension
* Other inclusions applied

Exclusion Criteria

* Patient with Secondary Hypertension
* Other exclusions applied
Minimum Eligible Age

19 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Addpharma Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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InHo Chae, M.D., Ph.D

Role: PRINCIPAL_INVESTIGATOR

Seoul National University Bundang Hospital

Locations

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Seoul National University Bundang Hospital

Seongnam-si, , South Korea

Site Status RECRUITING

Countries

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South Korea

Central Contacts

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JeongEun Park

Role: CONTACT

+82-31-891-6989

Facility Contacts

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InHo Chae

Role: primary

Other Identifiers

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AD-224P3

Identifier Type: -

Identifier Source: org_study_id

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