SOI Immediately vs Delayed

NCT ID: NCT06286579

Last Updated: 2024-02-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

70 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-03-01

Study Completion Date

2028-01-31

Brief Summary

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The aim of this randomized controlled trial is to compare the clinical and radiographic of immediately loaded, immediate (post-extractive, test group) versus delayed (control group) implants with new SOI surface

Detailed Description

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Conditions

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Dental Implant Dental Implant-Abutment Design

Keywords

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Dental Implant Immediately vs Delayes Implant-abutment connection

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomised controlled trial of parallel group design.
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors
One "blinded (when possible)" independent assessor

Study Groups

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Immediately implant placement

Atraumatic tooth extraction and immediately placement of implant with a new surface

Group Type EXPERIMENTAL

Immediately implant placement

Intervention Type DEVICE

After atraumatic tooth extraction immediate implant placement with SOI surface and loading will be performed with temporary restoration. After osseointegration (8 weeks), the temporary restoration will be modified according to the soft tissue management. After 3 to 4 months, a definitive digital or analog impression will be taken and later definitive restoration will be delivered

Delayed implant placement

Atraumatic tooth extraction, after the site will be left to heal for 4 months, just grafting with A-Oss and suture, according to a socket preservation procedure. Four month later, implant will be place

Group Type ACTIVE_COMPARATOR

Delayed

Intervention Type DEVICE

After atraumatic tooth extraction, the extraction site will be left to heal for 4 months, just grafting with A-Oss and suture, according to a socket preservation procedure. Four month later, implant will be place and immediate loadind with temporary restoration will be performed.

After osseointegration (8 weeks), the temporary restoration will be modified according to the soft tissue management. After 3 to 4 months, a definitive digital or analog impression will be taken and later definitive restoration will be delivered

Interventions

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Immediately implant placement

After atraumatic tooth extraction immediate implant placement with SOI surface and loading will be performed with temporary restoration. After osseointegration (8 weeks), the temporary restoration will be modified according to the soft tissue management. After 3 to 4 months, a definitive digital or analog impression will be taken and later definitive restoration will be delivered

Intervention Type DEVICE

Delayed

After atraumatic tooth extraction, the extraction site will be left to heal for 4 months, just grafting with A-Oss and suture, according to a socket preservation procedure. Four month later, implant will be place and immediate loadind with temporary restoration will be performed.

After osseointegration (8 weeks), the temporary restoration will be modified according to the soft tissue management. After 3 to 4 months, a definitive digital or analog impression will be taken and later definitive restoration will be delivered

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Any patient with at least one hopeless tooth in the mandible or maxilla, located between premolars, with intact post extractive alveolus. The implants must to engage at least 3 (mandible) to 5 (maxilla) mm of residual native bone over the socket.
* Patients with 18 years or older, and able to sign an informed consent.
* Smokers will be included and categorized into: 1) non smokers; 2) moderate smokers (smoking up to 10 cigarettes/day); 3) heavy smokers (smoking more than 11 cigarettes/day). Heavy smokers will be excluded.
* Biotype will be categorized in thin (≤1 mm), medium (\>1 - \<2 mm) or thick (≥2 mm).

Exclusion Criteria

* General contraindications to implant surgery.
* Patients irradiated in the head and neck area.
* Immunosuppressed or immunocompromised patients.
* Patients treated or under treatment with intravenous amino-bisphosphonates.
* Patients with untreated periodontitis.
* Patients with poor oral hygiene and motivation.
* Uncontrolled diabetes.
* Heavy smokers.
* Pregnancy or nursing.
* Substance abuser.
* Psychiatric problems or unrealistic expectations.
* Lack of opposite occluding dentition in the area intended for implant placement.
* Patients with infection and or inflammation in the area intended for implant placement.
* Patients participating in other studies, if the present protocol cannot be properly adhered to.
* Patients referred only for implant placement and cannot be followed ant the treating centre.
* Patients unable to be followed for 5 years
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Melodia, Dario, M.D.

INDIV

Sponsor Role collaborator

Pisano, Milena, M.D.

INDIV

Sponsor Role collaborator

Dr. Aurea M. I. Lumbau

UNKNOWN

Sponsor Role collaborator

Prof. Silvio Mario Meloni

UNKNOWN

Sponsor Role collaborator

Prof. Edoardo Baldoni

UNKNOWN

Sponsor Role collaborator

Università degli Studi di Sassari

OTHER

Sponsor Role lead

Responsible Party

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Marco Tallarico

Assistant professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Marco Tallarico

Sassari, , Italy

Site Status

Countries

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Italy

Other Identifiers

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UNISS_PHD_Osstem_3

Identifier Type: -

Identifier Source: org_study_id