A Study Using 18F-FAPI PET to Evaluate Treatment Response in Pancreatic Adenocarcinoma

NCT ID: NCT06277206

Last Updated: 2024-02-26

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 59 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2021-08-04
• Study Completion Date: 2024-02-10

Brief Summary

To explore the potential utility of 18F-FAPI-04 PET/CT for pathologic response evaluation to systemic treatment in PDAC

Conditions

18F-FAPI; Pancreas Adenocarcinoma; Systemic Treatment; Pathologic Response

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Interventions

18F-FAPI PET/CT

Enrolled patients underwent 18F-FAPI PET/CT at diagnosis. And preoperative 18F-FAPI PET/CT was completed in the patients met the criteria for conversion surgery after systemic treatment. The correlation between changes of parameters before and after treatment and pathologic response was analyzed.

Intervention Type: DIAGNOSTIC_TEST

Eligibility Criteria

Inclusion Criteria

• suspected to have pancreatic cancer by radiological imaging
• planned systemic treatment
• possibility of conversion surgery
• willingness to participate the study

Exclusion Criteria

• without pathologically confirmed pancreatic cancer
• poor performance status or organ functions that cannot meet the systemic treatment requirements
• metastatic disease
• pregnant patients

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 80 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Zhejiang University

OTHER

Sponsor Role: lead

Responsible Party

TingBo Liang

Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

First Affiliated Hospital, Medical College of Zhejiang University

Hangzhou, Zhejiang, China

Countries

China

Other Identifiers

FAPIPDAC02

Identifier Type: -

Identifier Source: org_study_id