A Study of Sex Differences in Neurocirculatory Control

NCT ID: NCT06261034

Last Updated: 2024-12-31

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-10-29

Study Completion Date

2027-03-31

Brief Summary

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The purpose of this study is to investigate potential sex differences in neurocirculatory control of blood pressure in patients with untreated obstructive sleep apnea (OSA).

Detailed Description

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Conditions

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Obstructive Sleep Apnea

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

* 20-70 years of age

Exclusion Criteria

* Coronary artery disease
* Heart failure
* Pregnancy
* COPD
* Diabetes
* CKD
* Sleep disorders other than OSA
* Shift workers
* Individuals who typically go to sleep after midnight
* Individuals who traveled across ≥2 time zones within one week of study visits
* BMI ≥40.0kg/m2
* Use of nicotine-containing products within the two years preceding study visits
* Use of allopurinol, proton pump inhibitors, or other medications/supplements which interfere with outcome measures
Minimum Eligible Age

20 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)

NIH

Sponsor Role collaborator

Mayo Clinic

OTHER

Sponsor Role lead

Responsible Party

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Joshua M. Bock

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Joshua Bock, PhD

Role: PRINCIPAL_INVESTIGATOR

Mayo Clinic

Locations

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Mayo Clinic in Rochester

Rochester, Minnesota, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Joshua Bock, PhD

Role: CONTACT

Phone: (507) 422-0768

Email: [email protected]

Ian Greenlund, PhD

Role: CONTACT

Phone: (507) 422-3411

Email: [email protected]

Facility Contacts

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Joshua Bock, PhD

Role: primary

Ian Greenlund, PhD

Role: backup

Other Identifiers

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8K12AR084222-15

Identifier Type: NIH

Identifier Source: secondary_id

View Link

23-008765

Identifier Type: -

Identifier Source: org_study_id