Targeted Navigation in Hepatocellular Carcinoma (HCC)

NCT ID: NCT06260943

Last Updated: 2025-07-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

100 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-04-15

Study Completion Date

2026-10-31

Brief Summary

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The investigators are trying to learn more about the personal perceptions and experiences regarding the needs of patients with liver cancer to help improve the care of all patients. The investigators would like to know whether there are needs that patients have or are aware of, especially those needs that the investigators have not been able to address. The investigators aim to develop a program that helps participants and participant's families to navigate the process of being diagnosed with liver cancer and receiving treatment.

Detailed Description

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Conditions

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Hepatocellular Carcinoma Cholangiocarcinoma Hepatobiliary Cancer

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Aim 3: Targeted Navigation Pilot Program

Participants in this group will be enrolled in a Targeted Navigation Pilot Program for up to 12 months.

Group Type EXPERIMENTAL

Target Navigation Pilot Program

Intervention Type BEHAVIORAL

Participants will meet with a navigator, in either English, Spanish or Creole, biweekly, in person or virtually, until the first treatment appointment and every three months after. Each session will last approximately one hour; depending on the needs identified, patients will be connected to appropriate institutional or community-based resources.

Interventions

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Target Navigation Pilot Program

Participants will meet with a navigator, in either English, Spanish or Creole, biweekly, in person or virtually, until the first treatment appointment and every three months after. Each session will last approximately one hour; depending on the needs identified, patients will be connected to appropriate institutional or community-based resources.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* HCC Patients:

* Enrolled or eligible for enrollment in Unified Prospective Registry and Biorepository of Patients with Chronic Liver Disease or Hepatobiliary Cancers Including Hepatocellular Carcinoma (HCC) and Cholangiocarcinoma.
* Diagnosis of hepatocellular carcinoma, confirmed by clinical chart review and International Classification of Diseases, Tenth Revision (ICD-10) C22.0.
* Adults, age 18 or older
* Able to provide informed consent
* All other interviewees:

* Advocates who will self-identify as having had HCC.
* Others who self-identify as either a caregiver or support person of an HCC patient.

Physicians/Licensed Independent Practitioners, Social Workers, Nurse Navigators, and Research Coordinators will all self-identify as being involved in the care of HCC patients.

Exclusion Criteria

* Unable to speak Spanish or English
* West Haven Grade 2 or higher hepatic encephalopathy19 or other cognitive impairment.
* Adults unable or unwilling to consent
* Individuals who are not yet adults (infants, children, teenagers)
* Prisoners
* Given that this study is minimal risk and there are no risks to a potential fetus, investigators will not exclude pregnant women; however, no data about pregnancy or their fetus is being collected
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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The V Foundation

OTHER

Sponsor Role collaborator

University of Miami

OTHER

Sponsor Role lead

Responsible Party

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Patricia Jones, MD

Associate Professor of Clinical Medicine

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Patricia Jones, MD

Role: PRINCIPAL_INVESTIGATOR

University of Miami

Locations

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University of Miami

Miami, Florida, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Gloria Figueroa

Role: CONTACT

(305) 243-0779

Patricia Jones, MD

Role: CONTACT

(305) 243-0779

Facility Contacts

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Gloria Figueroa

Role: primary

(305) 243-0779

Patricia Jones, MD

Role: backup

(305) 243-0779

Other Identifiers

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NCI-2024-00566

Identifier Type: REGISTRY

Identifier Source: secondary_id

20221220

Identifier Type: -

Identifier Source: org_study_id

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