Correlation of Antibody Response to COVID-19 Vaccination in Pregnant Woman and Transplacental Passage Into Cord Blood.

NCT ID: NCT06259656

Last Updated: 2024-07-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-10-25

Study Completion Date

2023-11-25

Brief Summary

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The goal of this study is to study the correlation of maternal and cord blood level of Anti SAR-CoV.

Detailed Description

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The goal of this study is to study the correlation of maternal and cord blood level of Anti SAR-CoV. Sample size is 40 Thai patients at labor room Vachira Phuket Hospital in October - November 2023, who have at least one COVID-19 vaccination before or when pregnant. The Secondary outcome is to study time effect after COVID-19 vaccination and effect of vaccine type on Antibody level.

Conditions

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Covid-19

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Thai term pregnant women are recruited at labor room, after informed consent was done. Characteristic data (such as vaccination type and time) and Maternal Blood was collected then cord blood was collected after birth. All blood was sent to test Anti SARs CoV antibody level. Then all data and 80 test result will analyzed.
Primary Study Purpose

HEALTH_SERVICES_RESEARCH

Blinding Strategy

NONE

Study Groups

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Thai term pregnant woman who have at least One dose of Covid vaccination

Maternal and cord blood was collected to test COVID-19 Spike Protein IgG Quantitative Antibody (CMIA)

Group Type OTHER

COVID-19 Spike Protein IgG Quantitative Antibody (CMIA)

Intervention Type DIAGNOSTIC_TEST

Maternal blood and cord blood were collected to test for COVID-19 Spike Protein IgG Quantitative Antibody (CMIA)

Interventions

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COVID-19 Spike Protein IgG Quantitative Antibody (CMIA)

Maternal blood and cord blood were collected to test for COVID-19 Spike Protein IgG Quantitative Antibody (CMIA)

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* Thai term pregnant women
* 18-45 year old
* At least 1 covid vaccination received
* admission at Vachira Phuket Hospital Labor Room

Exclusion Criteria

* Do not want to participate
* Unstable or Emergency condition
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

Yes

Sponsors

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Vachira Phuket Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Vachira Phuket Hospital

Phuket, , Thailand

Site Status

Countries

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Thailand

Other Identifiers

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VPH REC 009/2023

Identifier Type: -

Identifier Source: org_study_id

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