Hemianopsia Rehabilitation After Stroke or Brain Injury
NCT ID: NCT06241209
Last Updated: 2025-01-30
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
40 participants
INTERVENTIONAL
2024-01-25
2028-12-15
Brief Summary
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Detailed Description
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Hypothesis: Visual stimulation helps patients with visual pathway brain injury recover peripheral vision.
Justification: i) Axonal sprouting or re-rerouting can occur after brain injury ii) In Canada stroke prevalence comprises almost 900,000 patients. (Canada.ca, Health 2022). It is estimated that half of stroke survivors have a visual field deficit. (Rowe et al, PLoS One. 2019).
There is clinical equipoise regarding the results of vision therapy with visual stimulation. Romano JG, et al. Journal of the Neurological Sciences. 2008 Oct 15;273(1-2):70-4. versus Horton JC. Disappointing results from Nova Vision's visual restoration therapy. British Journal of Ophthalmology. 2005
Objectives: To determine the effect size of visual recovery, if any with computer screen visual stimulation
Research Method/Procedures
The project is prospective. Patients undergoing visual field testing found to have a hemianopsia will be invited to participate in the study. Chart review will be conducted on Connect Care. The following information will be collected: Patient age, sex, hand dominance, location and extent of stroke, number of prior strokes, time since initial/last stroke, neurologic diagnosis of neglect, perimetric findings, hours of television viewing, hours of smart phone use, hours of playing video games, smoking history, hypertension, diabetes mellitus, and hyperlipidemia.
Group 1 with an odd number year of birth will be asked to view 15 minutes of online news three days per week for 2 months. LIVE: Canadian News \| Weather \& Traffic - Latest Sports \| Breaking News (globalnews.ca)
Group 2 with an even number year of birth will be asked to view the 15-minute PowerPoint program three days per week for 2 months.
At the end of 2 months, the study groups will be asked to cross over for 2 months, and perimetry will be repeated at month 4 from study entry. If patients originally in Group 2 do not want to stop using the PowerPoint program, they will be allowed to drop out of the study.
A 24-degree Humphrey automated perimetry will be performed at study entry, month two and month four. The perimeter provides a visual field index (VFI) with scores ranging from zero (no perceived light) to 100 (normal).
PLAN FOR DATA ANALYSIS: For each patient, the VFI from both eyes will be averaged. The difference between the pre-intervention and post-intervention VFI's will be compared between the PowerPoint intervention versus observation groups after 2 months. The same analysis will be repeated after the cross-over.
Conditions
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Study Design
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NON_RANDOMIZED
CROSSOVER
TREATMENT
NONE
Study Groups
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Group 1 (online news)
Group 1 with an odd number year of birth will be asked to view 15 minutes of online news three days per week for 2 months. LIVE: Canadian News \| Weather \& Traffic - Latest Sports \| Breaking News (globalnews.ca)
No interventions assigned to this group
Group 2 (PowerPoint program)
Group 2 with an even number year of birth will be asked to view the 15-minute PowerPoint program three days per week for 2 months.
PowerPoint program visual stimulation
Moving objects, food, money, and other targets will be presented in the remaining seeing, and hemianopic areas.
Interventions
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PowerPoint program visual stimulation
Moving objects, food, money, and other targets will be presented in the remaining seeing, and hemianopic areas.
Eligibility Criteria
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Inclusion Criteria
Exclusion Criteria
18 Years
ALL
No
Sponsors
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University of Alberta
OTHER
Responsible Party
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Locations
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Eye Institute of Alberta, Royal Alexandra Hospital
Edmonton, Alberta, Canada
Countries
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Facility Contacts
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Related Links
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Related Info
Other Identifiers
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00134526
Identifier Type: -
Identifier Source: org_study_id
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