Long-term Home-based Exercise for Patients With COPD: the COPDtoParis Project

NCT ID: NCT06235502

Last Updated: 2024-12-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-11-01

Study Completion Date

2025-09-01

Brief Summary

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This randomised controlled trial (RCT) aims to investigate the effect of long-term, interactive home-based cycle-exercise on patients with Chronic Obstructive Pulmonary Disease (COPD) after a COPD exacerbation requiring hospitalisation. The investigators aim to investigate if patients can maintain or improve the effects of pulmonary rehabilitation in terms of walking distance, intensity of COPD symptoms, health related quality of life and Quality Adjusted Life-Years.

Participants will cycle on a pedal-exerciser in the comfort of staying in the participants' own home, whilst getting visual feedback from the 4Mvideo app. The 4Mvideo technology is a Danish designed software system, where users can cycle forward a recording of a cyclist by treading on a pedal-exerciser, thereby getting some of the experience of a real-life cycling trip at home.

The investigators will compare the clinical outcomes and daily activity levels with that of a control group consisting of COPD patients.

Detailed Description

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Patients with chronic obstructive pulmonary disease (COPD) have a higher risk of experiencing disability, and even though participating in pulmonary rehabilitation (PR) are efficient for regaining strength, function and relieving symptoms, effects prove difficult to maintain. Furthermore, physical attendance to outpatient PR is challenging for COPD patients, many of whom are bound to their home, due to said disability and symptoms. Even in patients who follow through with the PR programme, adherence to exercise after is a major challenge.

The investigators hypothesise that an intervention group of COPD-patients, who will receive home-based cycle exercise will maintain or even improve effects on physical fitness from PR, in terms of walking distance, daily activity levels (DAL), exercise tolerance, disease prevention and health related quality of life (HRQoL).

Furthermore, the investigators hypothesise that the participants express improved motivation in terms of adhering to exercise, when participating in home-based, interactive group cycle exercise.

It is expected to measure changes in DAL, lung function, levels of dyspnoea, exercise tolerance, walking distance, mobility, COPD symptoms, activity of daily living (ADL) related performance and HRQoL of the participants, along with assessing disease prevention. Data is compared intrapersonal and in-between groups to identify differences in outcomes at an individual level, and between intervention- and control group. Furthermore, the investigators expect to uncover identifiable in-depth insights into the values and beliefs towards exercising amongst participants.

40 participants are recruited amongst COPD patients that live in Aalborg Municipality and are admitted at Aalborg University Hospital, hospitalised due to acute exacerbation of COPD. After being discharged participants are referred to rehabilitation, for most in their own home. After rehabilitation participants are randomized into either intervention group who will exercise on exercise bikes connected with tablets in their own home. The control group will receive usual care, which consists of offers of exercising in their own home according to a programme or participating in exercise at a facility center.

Conditions

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Telerehabilitation COPD Quality of Life Mobility Limitation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized Controlled Trial
Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Participants
Participants are anonymised with a participant identification

Study Groups

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Home-based, longterm cycle-exercise

One year home-based cycle exercise on a exercise bike connected to a video app from where participants can cycle push videos forward when cycling.

Group Type EXPERIMENTAL

Home-based cycle-exercise for COPD patients

Intervention Type OTHER

Patients will cycle in their own home using a pedal exerciser connected to the 4M-video app

Standard of Care

Standard of Care; exercise at fitness center, home-based exercise according to programme, self-initiated exercise

Group Type ACTIVE_COMPARATOR

Standard of Care

Intervention Type OTHER

Exercise at Fitness Center, home based exercise according to a programme

Interventions

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Home-based cycle-exercise for COPD patients

Patients will cycle in their own home using a pedal exerciser connected to the 4M-video app

Intervention Type OTHER

Standard of Care

Exercise at Fitness Center, home based exercise according to a programme

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Adults at age \> 18 years old
* Hospital admission with COPD exacerbation with pre-existing COPD diagnosis
* Citizens of Aalborg Municipality
* Able to provide informed consent
* Accepting of referral to rehabilitation

Exclusion Criteria

* Terminal illness
* Unstable heart disease, i.e., ischemic heart disease, cardiac rhythm disorders
* Other conditions preventing participating in cycle exercise, e.g., amputation, regimens or earlier or upcoming surgeries preventing seated position, blindness
* Inability to understand basic Danish oral and written information or giving informed consent.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Karen Elise Jensen Foundation

OTHER

Sponsor Role collaborator

Simon Fougners Hartmann Family Foundation

UNKNOWN

Sponsor Role collaborator

4Mvideo

UNKNOWN

Sponsor Role collaborator

SENS Innovation Aps

UNKNOWN

Sponsor Role collaborator

Aalborg University Hospital

OTHER

Sponsor Role lead

Responsible Party

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Anna Lei Stoustrup

PhD Fellow

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Anna L Stoustrup, MSc

Role: PRINCIPAL_INVESTIGATOR

[email protected]

Locations

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Aalborg University Hospital

Aalborg, , Denmark

Site Status RECRUITING

Countries

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Denmark

Central Contacts

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Anna L Stoustrup, MSc

Role: CONTACT

+45 52505879

Ulla M Weinreich, PhD

Role: CONTACT

+45 30687526

Facility Contacts

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Anna L Stoustrup, MSc

Role: primary

+4520866747

Ulla M Weinreich, PhD, MD

Role: backup

References

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Stoustrup AL, Thomsen LP, Andreasen J, Palsson TS, Weinreich UM. Cluster randomised controlled trial on the effects of long-term home-based exercise for patients with chronic obstructive pulmonary disease with recent exacerbation: research protocol of the COPDtoParis Project. BMJ Open Respir Res. 2025 Jan 19;12(1):e002573. doi: 10.1136/bmjresp-2024-002573.

Reference Type DERIVED
PMID: 39832888 (View on PubMed)

Other Identifiers

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COPDtoParis

Identifier Type: -

Identifier Source: org_study_id