Paracetamol Effect on Prostaglandins and Blood Pressure
NCT ID: NCT06235320
Last Updated: 2025-02-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
72 participants
OBSERVATIONAL
2025-03-01
2026-09-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Paracetamol group
routine clinical treatment of pain with paracetamol or ibuprofen
No intervention beside clinical routine management
Ibuprofen group
routine clinical treatment of pain with paracetamol or ibuprofen
No intervention beside clinical routine management
Interventions
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routine clinical treatment of pain with paracetamol or ibuprofen
No intervention beside clinical routine management
Eligibility Criteria
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Inclusion Criteria
* Age 18 years or older
* Able to consent
* Patients with migraine type headache treated with paracetamol or ibuprofen within the last 12 hours or not treated with paracetamol or ibuprofen within the last 48 hours
* Patients treated with with paracetamol or ibuprofen undergoing orosurgery for wisedome tooth extraction
Exclusion Criteria
* Arterial hypertension
* Use of beta blockers
* Use of COX inhibitors other than paracetamol or ibuprofen, including low-dose acetylsalicylic acid
* Stable prophylactic therapy of migraine for less than 3 weeks
* Use of tryptans in the last two days (Frovatriptane in the last 6 days)
* Oral surgery patients using paracetamol or ibuprofen in the last 24 hours
* Known allergy to paracetamol or ibuprofen
18 Years
ALL
No
Sponsors
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Charite University, Berlin, Germany
OTHER
Responsible Party
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Engi Algharably
Dr.
Central Contacts
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Other Identifiers
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PIS-PaB
Identifier Type: -
Identifier Source: org_study_id
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