Peking University Birth Cohort in Weifang (PKUBC-WF)

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

2800 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-02-01

Study Completion Date

2043-12-31

Brief Summary

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The PKUBC-WF is a prospective cohort study carried out in Weifang city of Shandong, China. The primary aim of this study is to investigate the short-term and long-term effects of pre-pregnant and prenatal exposure on maternal and child health. Data are collected regarding environmental, nutritional and lifestyle exposures as well as short-term and long-term health outcomes of mothers and their children from birth to before 18 years old. Biological samples including peripheral blood, urine, placenta, umbilical cord, cord blood, and faeces are also collected.

Detailed Description

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Maternal and child health is of great concern globally. Early life phase of a fetus and infant is a critical period for the development of health and disease in the whole life. Exposure of negative environmental, nutritional and lifestyle factors in pregnant women during this period can have adverse effects on fetal and infant. In addition, for mothers, complications during pregnancy could also have a negative effect on long-term health of mothers, such as diabetes, hypertension. Thus, the Peking University Birth Cohort in Weifang is primarily aimed to investigate the short-term and long-term effects of pre-pregnant and prenatal exposure on maternal and child health. Data are collected regarding environmental, nutritional and lifestyle exposures as well as short-term and long-term health outcomes of mothers, husbands and their children from birth to before 18 years old. Biological samples including peripheral blood, urine, placenta, umbilical cord, cord blood, and faeces samples are also collected.

Conditions

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Health Problems in Pregnancy Pregnancy Outcomes Gestational Diabetes Gestational Hypertension Preterm Birth Obesity Mother-Infant Interaction Child Development Anemia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Exposure group

Group with environmental, nutritional or lifestyle exposures

No Interventions

Intervention Type OTHER

No intervention This is an observational study without any intervention

Non-exposed group

Group without any environmental, nutritional and lifestyle exposures

No interventions assigned to this group

Interventions

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No Interventions

No intervention This is an observational study without any intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Pregnant woman

1. Pregnant women, 6-13\^+6 gestational weeks
2. Resided in Weifang in the past half years and have no plan to move out after delivery
3. Pregnant women who plan to have antenatal care and delivery in Weifang maternal\&Child Hospital.
4. Pregnant women who is willing to participate in this study with informed consent
* Pregnant woman's husband

1. His wife was eligible for enrollment
2. He is the biological father of the child (his wife's current pregnancy)
3. Pregnant women's husband who is willing to participate in this study with informed consent

5\. Before the age of 8 years, his/her mother provided written informed consent. 6. After 8 years old, he/she agreed to continue this study and signed the informed consent.

Exclusion Criteria

* Participants who cannot communicate normally.

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Responsible Party

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Hai-Jun Wang

Prof.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Haijun Wang, Ph.D

Role: PRINCIPAL_INVESTIGATOR

Peking University

Locations

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