The Immediate Effect of Defocus Spectacles On the Choroid Thickness Using Optical Coherence Tomography on Children

NCT ID: NCT06234189

Last Updated: 2025-06-25

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

16 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-02-01

Study Completion Date

2024-03-07

Brief Summary

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The purpose is to examine temporary changes in the subfoveal choroid thickness after removal and after resumed use of Defocus Incorporated Multiple Segment Spectacle Lenses (DIMS).

Detailed Description

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Conditions

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Myopia

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Defocus Incorporated Multiple Segment Spectacle Lenses (DIMS)

Group Type EXPERIMENTAL

Defocus Incorporated Multiple Segment Spectacle Lenses (DIMS)

Intervention Type DEVICE

30 minutes without DIMS and 30 minutes with DIMS

Interventions

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Defocus Incorporated Multiple Segment Spectacle Lenses (DIMS)

30 minutes without DIMS and 30 minutes with DIMS

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Myopic children using Defocus Incorporated Multiple Segment Spectacle Lenses (DIMS) from the ongoing randomized clinical non-inferiority study: "Defocus Incorporated Multiple Segment (DIMS) Spectacle Lenses versus Orthokeratology lenses (OKL) for slowing myopia progression in children aged 6-12 years. A non-inferiority randomized clinical trial. The NISDO study" (ClinicalTrials.gov Identifier NCT05134935).
* Myopia at the time of inclusion in the NISDO study (inclusive): -2.00 to -4.75 D spherical component and up to -2.50 D of regular astigmatism (both eyes).
* Anisometropia at the time of inclusion in the NISDO study ≤ 1.50 D cycloplegic spherical equivalent refractive error.
* Best corrected visual acuity (inclusive) at the time of inclusion in the NISDO study: 0.8 Snellen (equivalent to ≥ 3/5 letter on the 0.8 line = 78 ETDRS letters).

Exclusion Criteria

* Manifest or intermittent squint.
* Contraindications to the use of OKL comprising (not exhaustive): keratoconus, chronic allergic conjunctivitis, and keratoconjunctivitis sicca.
* Previous eye surgery.
* Chronic eye disease demanding daily use of eye drops.
* Non-compliance to eye examinations (unstable fixation or anxiety towards contact lenses).
* Previous myopia control treatment.
Minimum Eligible Age

10 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Vejle Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Lou-Ann Andersen

Role: PRINCIPAL_INVESTIGATOR

Vejle Hospital

Locations

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The Ophthalmic department, Vejle Hospital

Vejle, Southern Denmark, Denmark

Site Status

Countries

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Denmark

Provided Documents

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Document Type: Statistical Analysis Plan

View Document

Other Identifiers

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TIDOCT

Identifier Type: -

Identifier Source: org_study_id

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