Epidemiological Data on Mast Cell Pathologies in France

NCT ID: NCT06186856

Last Updated: 2025-12-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

13000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-01-01

Study Completion Date

2038-12-31

Brief Summary

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Mast cell disorders constitute a heterogeneous group of diseases, including :

* mastocytosis, i.e. cutaneous, indolent and severe forms of the disease, such as aggressive mastocytosis and mast cell leukemia) ;
* mast cell-associated diseases such as mast cell activation syndrome (idiopathic, secondary or clonal), affecting both children and adults.

No epidemiological data are currently available in France.

In France, medical care of mast cell disorders is mainly provided by a rare disease network (CEREMAST), whose CRMR is located at the Necker Enfants Malades hospital in Paris. A total of 20 centers are located throughout France.

Our aim is to use this network to study patients suffering from these diseases. The overall aim of the study is to improve the understanding, diagnosis, prognosis, recognition and management of patients with mastocytosis.

Detailed Description

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Conditions

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Mast Cell Disorder

Keywords

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Mast Cell Disease Mastocytosis mast cell-associated diseases

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Patients

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. Children from birth and adults of any age
2. With one of the following mast cell diseases:

* Mastocytoses (cutaneous, systemic and sarcomas) Defined according to the WHO 2016 classification
* Mast cell activation syndromes (idiopathic, secondary and clonal)
* Other mast cell activation disorders (MCAD-NOS), Defined according to the Vienna classification
* Pre-mastocytosis or MMC (1 to 2 criteria according to WHO 2016 classification).
3. Managed in France in a rare disease reference, constitutive or competence center (CEREMAST) with DGOS labelization.

Exclusion Criteria

1\. Opposition of the patient or his/her parents to participation in the study.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Imagine Institute

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHU AMIENS site sud

Amiens, , France

Site Status RECRUITING

Chu Angers

Angers, , France

Site Status RECRUITING

Chu - Besancon

Besançon, , France

Site Status RECRUITING

Chu - Caen

Caen, , France

Site Status RECRUITING

Chu - Clermont Ferrand

Clermont-Ferrand, , France

Site Status RECRUITING

CHU Grenoble

Grenoble, , France

Site Status RECRUITING

Chru Lille

Lille, , France

Site Status RECRUITING

Chu - Limoges

Limoges, , France

Site Status RECRUITING

Hospices Civils de Lyon

Lyon, , France

Site Status RECRUITING

Chu - La Timone - Marseille

Marseille, , France

Site Status RECRUITING

CHU de Montpellier

Montpellier, , France

Site Status RECRUITING

CHU de NANCY

Nancy, , France

Site Status RECRUITING

Chu - Nantes

Nantes, , France

Site Status RECRUITING

Hôpital Universitaire Pitié Salpetrière

Paris, , France

Site Status RECRUITING

Hôpital Necker-Enfants malades

Paris, , France

Site Status RECRUITING

Chu - Rennes

Rennes, , France

Site Status RECRUITING

CHU Réunion sud - Saint Pierre

Saint-Pierre, , France

Site Status RECRUITING

Chru - Strasbourg

Strasbourg, , France

Site Status RECRUITING

CHU Purpan

Toulouse, , France

Site Status RECRUITING

CHU de TOURS

Tours, , France

Site Status NOT_YET_RECRUITING

Countries

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France

Central Contacts

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Julien Rossignol, Dr

Role: CONTACT

Phone: +33 (0)1 44 49 40 00

Email: [email protected]

Facility Contacts

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Clément GOURGUECHON, Dr

Role: primary

Christian Lavigne, Dr

Role: primary

Florence CASTELAIN, Dr

Role: primary

Gandhi DAMAJ, Pr

Role: primary

Yann OLLIVIER, Dr

Role: backup

Olivier TOURNILHAC, Pr

Role: primary

Laurence BOUILLET, Pr

Role: primary

David LAUNAY, Pr

Role: primary

Marie-Pierre GOURIN, Dr

Role: primary

Maël Heiblig, Dr

Role: primary

Caroline GAUDY, Pr

Role: primary

Philippe GUILPAIN, Pr

Role: primary

Roland JAUSSAUD, Pr

Role: primary

Antoine NEEL, Pr

Role: primary

Stephane Barete, Dr

Role: primary

Julien Rossignol, Dr

Role: primary

Hassiba Bouktit

Role: backup

Edwige LE MOUEL, Dr

Role: primary

Quentin CABRERA, Dr

Role: primary

Rose-Marie JAVIER, Dr

Role: primary

Cristina LIVIDEANU, Dr

Role: primary

Cyrille HOARAU, Dr

Role: primary

Other Identifiers

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HJ-22-DATAMAST

Identifier Type: -

Identifier Source: org_study_id